Finan P - Search Results

1

Essential role for the p110delta phosphoinositide 3-kinase in the allergic response.

Ali K, Bilancio A, Thomas M, Pearce W, Gilfillan AM, Tkaczyk C, Kuehn N, Gray A, Giddings J, Peskett E, Fox R, Bruce I, Walker C, Sawyer C, Okkenhaug K, Finan P, Vanhaesebroeck B. Ali K, et al. Among authors: finan p. Nature. 2004 Oct 21;431(7011):1007-11. doi: 10.1038/nature02991. Nature. 2004. PMID: 15496927 Free article.

2

PI 3-kinase inhibition: a therapeutic target for respiratory disease.

Finan PM, Thomas MJ. Finan PM, et al. Biochem Soc Trans. 2004 Apr;32(Pt 2):378-82. doi: 10.1042/bst0320378. Biochem Soc Trans. 2004. PMID: 15046612 Review.

3

Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases.

Thomas MJ, Smith A, Head DH, Milne L, Nicholls A, Pearce W, Vanhaesebroeck B, Wymann MP, Hirsch E, Trifilieff A, Walker C, Finan P, Westwick J. Thomas MJ, et al. Among authors: finan p. Eur J Immunol. 2005 Apr;35(4):1283-91. doi: 10.1002/eji.200425634. Eur J Immunol. 2005. PMID: 15739165 Free article.

4

Genetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels.

Harris SJ, Ciuclan L, Finan PM, Wymann MP, Walker C, Westwick J, Ward SG, Thomas MJ. Harris SJ, et al. Among authors: finan pm. Eur J Immunol. 2012 Dec;42(12):3394-404. doi: 10.1002/eji.201242463. Epub 2012 Oct 1. Eur J Immunol. 2012. PMID: 22930133 Free article.

5

Essential role of phosphoinositide 3-kinase gamma in eosinophil chemotaxis within acute pulmonary inflammation.

Thomas M, Edwards MJ, Sawicka E, Duggan N, Hirsch E, Wymann MP, Owen C, Trifilieff A, Walker C, Westwick J, Finan P. Thomas M, et al. Among authors: finan p. Immunology. 2009 Mar;126(3):413-22. doi: 10.1111/j.1365-2567.2008.02908.x. Epub 2008 Aug 27. Immunology. 2009. PMID: 18754810 Free PMC article.

6

Therapeutic potential of phosphoinositide 3-kinase inhibitors.

Ward S, Sotsios Y, Dowden J, Bruce I, Finan P. Ward S, et al. Among authors: finan p. Chem Biol. 2003 Mar;10(3):207-13. doi: 10.1016/s1074-5521(03)00048-6. Chem Biol. 2003. PMID: 12670534 Review.

7

PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.

Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L. Ferguson GJ, et al. Among authors: finan p. Nat Cell Biol. 2007 Jan;9(1):86-91. doi: 10.1038/ncb1517. Epub 2006 Dec 17. Nat Cell Biol. 2007. PMID: 17173040

8

Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway.

Bruce I, Akhlaq M, Bloomfield GC, Budd E, Cox B, Cuenoud B, Finan P, Gedeck P, Hatto J, Hayler JF, Head D, Keller T, Kirman L, Leblanc C, Le Grand D, McCarthy C, O'Connor D, Owen C, Oza MS, Pilgrim G, Press NE, Sviridenko L, Whitehead L. Bruce I, et al. Among authors: finan p. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5445-50. doi: 10.1016/j.bmcl.2012.07.042. Epub 2012 Jul 17. Bioorg Med Chem Lett. 2012. PMID: 22863202

9

Phosphoinositide 3-kinase gamma is an essential amplifier of mast cell function.

Laffargue M, Calvez R, Finan P, Trifilieff A, Barbier M, Altruda F, Hirsch E, Wymann MP. Laffargue M, et al. Among authors: finan p. Immunity. 2002 Mar;16(3):441-51. doi: 10.1016/s1074-7613(02)00282-0. Immunity. 2002. PMID: 11911828 Free article.

10

Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents.

Ward SG, Finan P. Ward SG, et al. Among authors: finan p. Curr Opin Pharmacol. 2003 Aug;3(4):426-34. doi: 10.1016/s1471-4892(03)00078-x. Curr Opin Pharmacol. 2003. PMID: 12901953 Review.

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