Mayhood T - Search Results

1

Differential type 4 cAMP-specific phosphodiesterase (PDE4) expression and functional sensitivity to PDE4 inhibitors among rats, monkeys and humans.

Bian H, Zhang J, Wu P, Varty LA, Jia Y, Mayhood T, Hey JA, Wang P. Bian H, et al. Among authors: mayhood t. Biochem Pharmacol. 2004 Dec 1;68(11):2229-36. doi: 10.1016/j.bcp.2004.08.014. Biochem Pharmacol. 2004. PMID: 15498513

2

Structure-guided discovery of cyclin-dependent kinase inhibitors.

Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V. Fischmann TO, et al. Among authors: mayhood t. Biopolymers. 2008 May;89(5):372-9. doi: 10.1002/bip.20868. Biopolymers. 2008. PMID: 17937404

3

NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA.

Hou Y, Mayhood T, Sheth P, Tan CM, Labroli M, Su J, Wyss DF, Roemer T, McCoy MA. Hou Y, et al. Among authors: mayhood t. J Biomol Screen. 2016 Jul;21(6):579-89. doi: 10.1177/1087057116640199. Epub 2016 Mar 29. J Biomol Screen. 2016. PMID: 27028606

4

Ligand binding affinity determined by temperature-dependent circular dichroism: cyclin-dependent kinase 2 inhibitors.

Mayhood TW, Windsor WT. Mayhood TW, et al. Anal Biochem. 2005 Oct 15;345(2):187-97. doi: 10.1016/j.ab.2005.07.032. Anal Biochem. 2005. PMID: 16140252

5

Fluorescence polarization assay and inhibitor design for MDM2/p53 interaction.

Zhang R, Mayhood T, Lipari P, Wang Y, Durkin J, Syto R, Gesell J, McNemar C, Windsor W. Zhang R, et al. Among authors: mayhood t. Anal Biochem. 2004 Aug 1;331(1):138-46. doi: 10.1016/j.ab.2004.03.009. Anal Biochem. 2004. PMID: 15246006

6

Expression and purification of phosphorylated and non-phosphorylated human MEK1.

Smith CK, Carr D, Mayhood TW, Jin W, Gray K, Windsor WT. Smith CK, et al. Among authors: mayhood tw. Protein Expr Purif. 2007 Apr;52(2):446-56. doi: 10.1016/j.pep.2006.11.002. Epub 2006 Nov 9. Protein Expr Purif. 2007. PMID: 17175166

7

Development of a fluorescence polarization bead-based coupled assay to target different activity/conformation states of a protein kinase.

Lu Z, Yin Z, James L, Syto R, Stafford JM, Koseoglu S, Mayhood T, Myers J, Windsor W, Kirschmeier P, Samatar AA, Malcolm B, Turek-Etienne TC, Kumar CC. Lu Z, et al. Among authors: mayhood t. J Biomol Screen. 2004 Jun;9(4):309-21. doi: 10.1177/1087057104263506. J Biomol Screen. 2004. PMID: 15191648

8

Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.

Wang H, Mann PA, Xiao L, Gill C, Galgoci AM, Howe JA, Villafania A, Barbieri CM, Malinverni JC, Sher X, Mayhood T, McCurry MD, Murgolo N, Flattery A, Mack M, Roemer T. Wang H, et al. Among authors: mayhood t. Cell Chem Biol. 2017 May 18;24(5):576-588.e6. doi: 10.1016/j.chembiol.2017.03.014. Epub 2017 Apr 20. Cell Chem Biol. 2017. PMID: 28434876 Free article.

9

Benzimidazole analogs as WTA biosynthesis inhibitors targeting methicillin resistant Staphylococcus aureus.

Yang SW, Pan J, Yang C, Labroli M, Pan W, Caldwell J, Ha S, Koseoglu S, Xiao JC, Mayhood T, Sheth PR, Garlisi CG, Wu J, Lee SH, Wang H, Tan CM, Roemer T, Su J. Yang SW, et al. Among authors: mayhood t. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4743-4747. doi: 10.1016/j.bmcl.2016.08.036. Epub 2016 Aug 16. Bioorg Med Chem Lett. 2016. PMID: 27575474

10

Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors.

Fischmann TO, Smith CK, Mayhood TW, Myers JE, Reichert P, Mannarino A, Carr D, Zhu H, Wong J, Yang RS, Le HV, Madison VS. Fischmann TO, et al. Biochemistry. 2009 Mar 31;48(12):2661-74. doi: 10.1021/bi801898e. Biochemistry. 2009. PMID: 19161339

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