ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization.
Zhang L, Cheng HH, Krüger N, Hörnich B, Graichen L, Hahn AS, Schulz SR, Jäck HM, Stankov MV, Behrens GMN, Müller MA, Drosten C, Mörer O, Winkler MS, Qian Z, Pöhlmann S, Hoffmann M.
Zhang L, et al. Among authors: cheng hh.
PLoS Pathog. 2024 Nov 13;20(11):e1012653. doi: 10.1371/journal.ppat.1012653. eCollection 2024 Nov.
PLoS Pathog. 2024.
PMID: 39536058