de Groot PG - Search Results

1

IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis.

de Laat B, Derksen RH, Urbanus RT, de Groot PG. de Laat B, et al. Among authors: de groot pg. Blood. 2005 Feb 15;105(4):1540-5. doi: 10.1182/blood-2004-09-3387. Epub 2004 Oct 26. Blood. 2005. PMID: 15507529 Free article.

2

Oral anticoagulation reduces activated protein C less than protein C and other vitamin K-dependent clotting factors.

Simmelink MJ, de Groot PG, Derksen RH, Fernandez JA, Griffin JH. Simmelink MJ, et al. Among authors: de groot pg. Blood. 2002 Dec 1;100(12):4232-3. doi: 10.1182/blood-2002-01-0329. Epub 2002 Aug 8. Blood. 2002. PMID: 12393585 Free article.

3

beta 2 Glycoprotein I--a key player in the antiphospholipid syndrome.

Lutters BC, de Groot PG, Derksen RH. Lutters BC, et al. Among authors: de groot pg. Isr Med Assoc J. 2002 Nov;4(11 Suppl):958-62. Isr Med Assoc J. 2002. PMID: 12455190 Review. No abstract available.

4

beta2-glycoprotein I, the playmaker of the antiphospholipid syndrome.

Bas de Laat H, Derksen RH, de Groot PG. Bas de Laat H, et al. Among authors: de groot pg. Clin Immunol. 2004 Aug;112(2):161-8. doi: 10.1016/j.clim.2004.02.012. Clin Immunol. 2004. PMID: 15240159 Review.

5

beta2-glycoprotein I-dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome.

de Laat HB, Derksen RH, Urbanus RT, Roest M, de Groot PG. de Laat HB, et al. Among authors: de groot pg. Blood. 2004 Dec 1;104(12):3598-602. doi: 10.1182/blood-2004-03-1107. Epub 2004 Aug 17. Blood. 2004. PMID: 15315975 Free article.

6

The binding site in {beta}2-glycoprotein I for ApoER2' on platelets is located in domain V.

van Lummel M, Pennings MT, Derksen RH, Urbanus RT, Lutters BC, Kaldenhoven N, de Groot PG. van Lummel M, et al. Among authors: de groot pg. J Biol Chem. 2005 Nov 4;280(44):36729-36. doi: 10.1074/jbc.M504172200. Epub 2005 Aug 9. J Biol Chem. 2005. PMID: 16091370 Free article.

7

Pathogenic anti-beta2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a conformational change.

de Laat B, Derksen RH, van Lummel M, Pennings MT, de Groot PG. de Laat B, et al. Among authors: de groot pg. Blood. 2006 Mar 1;107(5):1916-24. doi: 10.1182/blood-2005-05-1943. Epub 2005 Nov 3. Blood. 2006. PMID: 16269621 Free article.

8

Correlation between antiphospholipid antibodies that recognize domain I of beta2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5.

de Laat B, Wu XX, van Lummel M, Derksen RH, de Groot PG, Rand JH. de Laat B, et al. Among authors: de groot pg. Blood. 2007 Feb 15;109(4):1490-4. doi: 10.1182/blood-2006-07-030148. Epub 2006 Oct 19. Blood. 2007. PMID: 17053060 Free article.

9

beta2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation.

Hulstein JJ, Lenting PJ, de Laat B, Derksen RH, Fijnheer R, de Groot PG. Hulstein JJ, et al. Among authors: de laat b, de groot pg. Blood. 2007 Sep 1;110(5):1483-91. doi: 10.1182/blood-2006-10-053199. Epub 2007 May 8. Blood. 2007. PMID: 17488878 Free article. Clinical Trial.

10

Current insight into diagnostics and pathophysiology of the antiphospolipid syndrome.

Urbanus RT, Derksen RH, de Groot PG. Urbanus RT, et al. Among authors: de groot pg. Blood Rev. 2008 Mar;22(2):93-105. doi: 10.1016/j.blre.2007.09.001. Epub 2007 Oct 25. Blood Rev. 2008. PMID: 17964017 Review.

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