Lopaschuk GD - Search Results

1

Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition.

Sheth SS, Castellani LW, Chari S, Wagg C, Thipphavong CK, Bodnar JS, Tontonoz P, Attie AD, Lopaschuk GD, Lusis AJ. Sheth SS, et al. Among authors: lopaschuk gd. J Lipid Res. 2005 Jan;46(1):123-34. doi: 10.1194/jlr.M400341-JLR200. Epub 2004 Nov 1. J Lipid Res. 2005. PMID: 15520447 Free article.

2

Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia.

Kuang M, Febbraio M, Wagg C, Lopaschuk GD, Dyck JR. Kuang M, et al. Among authors: lopaschuk gd. Circulation. 2004 Mar 30;109(12):1550-7. doi: 10.1161/01.CIR.0000121730.41801.12. Epub 2004 Mar 15. Circulation. 2004. PMID: 15023869

3

Chronic activation of PPARalpha is detrimental to cardiac recovery after ischemia.

Sambandam N, Morabito D, Wagg C, Finck BN, Kelly DP, Lopaschuk GD. Sambandam N, et al. Among authors: lopaschuk gd. Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H87-95. doi: 10.1152/ajpheart.00285.2005. Epub 2005 Sep 9. Am J Physiol Heart Circ Physiol. 2006. PMID: 16155108 Free article.

4

Alpha-lipoic acid increases cardiac glucose oxidation independent of AMP-activated protein kinase in isolated working rat hearts.

Onay-Besikci A, Wagg C, Lopaschuk TP, Keung W, Lopaschuk GD. Onay-Besikci A, et al. Among authors: lopaschuk tp, lopaschuk gd. Basic Res Cardiol. 2007 Sep;102(5):436-44. doi: 10.1007/s00395-007-0661-4. Epub 2007 May 29. Basic Res Cardiol. 2007. PMID: 17530314

5

Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation.

Zhang L, Ussher JR, Oka T, Cadete VJ, Wagg C, Lopaschuk GD. Zhang L, et al. Among authors: lopaschuk gd. Cardiovasc Res. 2011 Jan 1;89(1):148-56. doi: 10.1093/cvr/cvq266. Epub 2010 Aug 20. Cardiovasc Res. 2011. PMID: 20729341

6

Elevated levels of activated NHE1 protect the myocardium and improve metabolism following ischemia/reperfusion injury.

Mraiche F, Wagg CS, Lopaschuk GD, Fliegel L. Mraiche F, et al. Among authors: lopaschuk gd. J Mol Cell Cardiol. 2011 Jan;50(1):157-64. doi: 10.1016/j.yjmcc.2010.10.016. Epub 2010 Oct 23. J Mol Cell Cardiol. 2011. PMID: 20974148

7

Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.

Chambers KT, Leone TC, Sambandam N, Kovacs A, Wagg CS, Lopaschuk GD, Finck BN, Kelly DP. Chambers KT, et al. Among authors: lopaschuk gd. J Biol Chem. 2011 Apr 1;286(13):11155-62. doi: 10.1074/jbc.M110.217349. Epub 2011 Feb 14. J Biol Chem. 2011. PMID: 21321124 Free PMC article.

8

Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding.

Zhang L, Mori J, Wagg C, Lopaschuk GD. Zhang L, et al. Among authors: lopaschuk gd. FEBS Lett. 2012 Apr 5;586(7):996-1003. doi: 10.1016/j.febslet.2012.02.027. Epub 2012 Mar 3. FEBS Lett. 2012. PMID: 22569253 Free article.

9

ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4.

Mori J, Alrob OA, Wagg CS, Harris RA, Lopaschuk GD, Oudit GY. Mori J, et al. Among authors: lopaschuk gd. Am J Physiol Heart Circ Physiol. 2013 Apr 15;304(8):H1103-13. doi: 10.1152/ajpheart.00636.2012. Epub 2013 Feb 8. Am J Physiol Heart Circ Physiol. 2013. PMID: 23396452 Free article.

10

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

Alrob OA, Sankaralingam S, Ma C, Wagg CS, Fillmore N, Jaswal JS, Sack MN, Lehner R, Gupta MP, Michelakis ED, Padwal RS, Johnstone DE, Sharma AM, Lopaschuk GD. Alrob OA, et al. Among authors: lopaschuk gd. Cardiovasc Res. 2014 Sep 1;103(4):485-97. doi: 10.1093/cvr/cvu156. Epub 2014 Jun 25. Cardiovasc Res. 2014. PMID: 24966184 Free PMC article.

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