Agger K - Search Results

1

A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner.

Attwooll C, Oddi S, Cartwright P, Prosperini E, Agger K, Steensgaard P, Wagener C, Sardet C, Moroni MC, Helin K. Attwooll C, et al. Among authors: agger k. J Biol Chem. 2005 Jan 14;280(2):1199-208. doi: 10.1074/jbc.M412509200. Epub 2004 Nov 8. J Biol Chem. 2005. PMID: 15536069 Free article.

2

Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.

Agger K, Santoni-Rugiu E, Holmberg C, Karlström O, Helin K. Agger K, et al. Oncogene. 2005 Jan 27;24(5):780-9. doi: 10.1038/sj.onc.1208248. Oncogene. 2005. PMID: 15531911

3

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3.

Cloos PA, Christensen J, Agger K, Maiolica A, Rappsilber J, Antal T, Hansen KH, Helin K. Cloos PA, et al. Among authors: agger k. Nature. 2006 Jul 20;442(7100):307-11. doi: 10.1038/nature04837. Epub 2006 May 28. Nature. 2006. PMID: 16732293

4

The emerging functions of histone demethylases.

Agger K, Christensen J, Cloos PA, Helin K. Agger K, et al. Curr Opin Genet Dev. 2008 Apr;18(2):159-68. doi: 10.1016/j.gde.2007.12.003. Epub 2008 Feb 20. Curr Opin Genet Dev. 2008. PMID: 18281209 Review.

5

Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease.

Cloos PA, Christensen J, Agger K, Helin K. Cloos PA, et al. Among authors: agger k. Genes Dev. 2008 May 1;22(9):1115-40. doi: 10.1101/gad.1652908. Genes Dev. 2008. PMID: 18451103 Free PMC article. Review.

6

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

Pasini D, Hansen KH, Christensen J, Agger K, Cloos PA, Helin K. Pasini D, et al. Among authors: agger k. Genes Dev. 2008 May 15;22(10):1345-55. doi: 10.1101/gad.470008. Genes Dev. 2008. PMID: 18483221 Free PMC article.

7

Regulation of stem cell differentiation by histone methyltransferases and demethylases.

Pasini D, Bracken AP, Agger K, Christensen J, Hansen K, Cloos PA, Helin K. Pasini D, et al. Among authors: agger k. Cold Spring Harb Symp Quant Biol. 2008;73:253-63. doi: 10.1101/sqb.2008.73.009. Epub 2008 Nov 6. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19022750 Free article. Review.

8

Inhibitors of histone demethylases.

Lohse B, Kristensen JL, Kristensen LH, Agger K, Helin K, Gajhede M, Clausen RP. Lohse B, et al. Among authors: agger k. Bioorg Med Chem. 2011 Jun 15;19(12):3625-36. doi: 10.1016/j.bmc.2011.01.046. Epub 2011 Feb 1. Bioorg Med Chem. 2011. PMID: 21596573 Review.

9

Histone lysine demethylases as targets for anticancer therapy.

Højfeldt JW, Agger K, Helin K. Højfeldt JW, et al. Among authors: agger k. Nat Rev Drug Discov. 2013 Dec;12(12):917-30. doi: 10.1038/nrd4154. Epub 2013 Nov 15. Nat Rev Drug Discov. 2013. PMID: 24232376 Review.

10

The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development.

Pedersen MT, Agger K, Laugesen A, Johansen JV, Cloos PA, Christensen J, Helin K. Pedersen MT, et al. Among authors: agger k. Mol Cell Biol. 2014 Mar;34(6):1031-45. doi: 10.1128/MCB.00864-13. Epub 2014 Jan 6. Mol Cell Biol. 2014. PMID: 24396064 Free PMC article.

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