Nayyar A - Search Results

1

Ring-substituted quinolines. Part 2: Synthesis and antimycobacterial activities of ring-substituted quinolinecarbohydrazide and ring-substituted quinolinecarboxamide analogues.

Monga V, Nayyar A, Vaitilingam B, Palde PB, Jhamb SS, Kaur S, Singh PP, Jain R. Monga V, et al. Among authors: nayyar a. Bioorg Med Chem. 2004 Dec 15;12(24):6465-72. doi: 10.1016/j.bmc.2004.09.017. Bioorg Med Chem. 2004. PMID: 15556764

2

Substituted 4-methylquinolines as a new class of anti-tuberculosis agents.

Jain R, Vaitilingam B, Nayyar A, Palde PB. Jain R, et al. Among authors: nayyar a. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1051-4. doi: 10.1016/s0960-894x(03)00074-x. Bioorg Med Chem Lett. 2003. PMID: 12643909

3

Synthesis and antimycobacterial activities of ring-substituted quinolinecarboxylic acid/ester analogues. Part 1.

Vaitilingam B, Nayyar A, Palde PB, Monga V, Jain R, Kaur S, Singh PP. Vaitilingam B, et al. Among authors: nayyar a. Bioorg Med Chem. 2004 Aug 1;12(15):4179-88. doi: 10.1016/j.bmc.2004.05.018. Bioorg Med Chem. 2004. PMID: 15246094

4

3D-QSAR study of ring-substituted quinoline class of anti-tuberculosis agents.

Nayyar A, Malde A, Jain R, Coutinho E. Nayyar A, et al. Bioorg Med Chem. 2006 Feb 1;14(3):847-56. doi: 10.1016/j.bmc.2005.09.018. Epub 2005 Oct 7. Bioorg Med Chem. 2006. PMID: 16214351

5

Synthesis, anti-tuberculosis activity, and 3D-QSAR study of ring-substituted-2/4-quinolinecarbaldehyde derivatives.

Nayyar A, Malde A, Coutinho E, Jain R. Nayyar A, et al. Bioorg Med Chem. 2006 Nov 1;14(21):7302-10. doi: 10.1016/j.bmc.2006.06.049. Epub 2006 Jul 14. Bioorg Med Chem. 2006. PMID: 16843663

6

Synthesis, anti-tuberculosis activity, and 3D-QSAR study of 4-(adamantan-1-yl)-2-substituted quinolines.

Nayyar A, Monga V, Malde A, Coutinho E, Jain R. Nayyar A, et al. Bioorg Med Chem. 2007 Jan 15;15(2):626-40. doi: 10.1016/j.bmc.2006.10.064. Epub 2006 Nov 1. Bioorg Med Chem. 2007. PMID: 17107805

7

Synthesis, anti-tuberculosis activity and 3D-QSAR study of amino acid conjugates of 4-(adamantan-1-yl) group containing quinolines.

Nayyar A, Patel SR, Shaikh M, Coutinho E, Jain R. Nayyar A, et al. Eur J Med Chem. 2009 May;44(5):2017-29. doi: 10.1016/j.ejmech.2008.10.004. Epub 2008 Oct 11. Eur J Med Chem. 2009. PMID: 19022537

8

Recent advances in new structural classes of anti-tuberculosis agents.

Nayyar A, Jain R. Nayyar A, et al. Curr Med Chem. 2005;12(16):1873-86. doi: 10.2174/0929867054546654. Curr Med Chem. 2005. PMID: 16101507 Review.

9

Structure-activity relationships of antitubercular nitroimidazoles. 3. Exploration of the linker and lipophilic tail of ((s)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-amino PA-824).

Cherian J, Choi I, Nayyar A, Manjunatha UH, Mukherjee T, Lee YS, Boshoff HI, Singh R, Ha YH, Goodwin M, Lakshminarayana SB, Niyomrattanakit P, Jiricek J, Ravindran S, Dick T, Keller TH, Dartois V, Barry CE 3rd. Cherian J, et al. Among authors: nayyar a. J Med Chem. 2011 Aug 25;54(16):5639-59. doi: 10.1021/jm1010644. Epub 2011 Jul 26. J Med Chem. 2011. PMID: 21755942 Free PMC article.

10

Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles.

Gurumurthy M, Mukherjee T, Dowd CS, Singh R, Niyomrattanakit P, Tay JA, Nayyar A, Lee YS, Cherian J, Boshoff HI, Dick T, Barry CE 3rd, Manjunatha UH. Gurumurthy M, et al. Among authors: nayyar a. FEBS J. 2012 Jan;279(1):113-25. doi: 10.1111/j.1742-4658.2011.08404.x. Epub 2011 Nov 14. FEBS J. 2012. PMID: 22023140 Free PMC article.

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