Alessi DR - Search Results

1

Analysis of the LKB1-STRAD-MO25 complex.

Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR. Boudeau J, et al. Among authors: alessi dr. J Cell Sci. 2004 Dec 15;117(Pt 26):6365-75. doi: 10.1242/jcs.01571. Epub 2004 Nov 23. J Cell Sci. 2004. PMID: 15561763

2

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

Alessi DR, Deak M, Casamayor A, Caudwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A, Bownes M. Alessi DR, et al. Curr Biol. 1997 Oct 1;7(10):776-89. doi: 10.1016/s0960-9822(06)00336-8. Curr Biol. 1997. PMID: 9368760 Free article.

3

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: alessi dr. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

4

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

Deak M, Clifton AD, Lucocq LM, Alessi DR. Deak M, et al. Among authors: alessi dr. EMBO J. 1998 Aug 3;17(15):4426-41. doi: 10.1093/emboj/17.15.4426. EMBO J. 1998. PMID: 9687510 Free PMC article.

5

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J. Currie RA, et al. Among authors: alessi dr. Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):575-83. Biochem J. 1999. PMID: 9895304 Free PMC article.

6

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

Balendran A, Casamayor A, Deak M, Paterson A, Gaffney P, Currie R, Downes CP, Alessi DR. Balendran A, et al. Among authors: alessi dr. Curr Biol. 1999 Apr 22;9(8):393-404. doi: 10.1016/s0960-9822(99)80186-9. Curr Biol. 1999. PMID: 10226025 Free article.

7

Characterisation of a plant 3-phosphoinositide-dependent protein kinase-1 homologue which contains a pleckstrin homology domain.

Deak M, Casamayor A, Currie RA, Downes CP, Alessi DR. Deak M, et al. Among authors: alessi dr. FEBS Lett. 1999 May 28;451(3):220-6. doi: 10.1016/s0014-5793(99)00556-6. FEBS Lett. 1999. PMID: 10371193 Free article.

8

Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B.

Bertrand L, Alessi DR, Deprez J, Deak M, Viaene E, Rider MH, Hue L. Bertrand L, et al. Among authors: alessi dr. J Biol Chem. 1999 Oct 22;274(43):30927-33. doi: 10.1074/jbc.274.43.30927. J Biol Chem. 1999. PMID: 10521487 Free article.

9

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA.

Biondi RM, Cheung PC, Casamayor A, Deak M, Currie RA, Alessi DR. Biondi RM, et al. Among authors: alessi dr. EMBO J. 2000 Mar 1;19(5):979-88. doi: 10.1093/emboj/19.5.979. EMBO J. 2000. PMID: 10698939 Free PMC article.

10

A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1.

Balendran A, Biondi RM, Cheung PC, Casamayor A, Deak M, Alessi DR. Balendran A, et al. Among authors: alessi dr. J Biol Chem. 2000 Jul 7;275(27):20806-13. doi: 10.1074/jbc.M000421200. J Biol Chem. 2000. PMID: 10764742 Free article.

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