Boudeau J - Search Results

1

Analysis of the LKB1-STRAD-MO25 complex.

Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR. Boudeau J, et al. J Cell Sci. 2004 Dec 15;117(Pt 26):6365-75. doi: 10.1242/jcs.01571. Epub 2004 Nov 23. J Cell Sci. 2004. PMID: 15561763

2

Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.

Boudeau J, Kieloch A, Alessi DR, Stella A, Guanti G, Resta N. Boudeau J, et al. Hum Mutat. 2003 Feb;21(2):172. doi: 10.1002/humu.9112. Hum Mutat. 2003. PMID: 12552571

3

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

Sapkota GP, Boudeau J, Deak M, Kieloch A, Morrice N, Alessi DR. Sapkota GP, et al. Among authors: boudeau j. Biochem J. 2002 Mar 1;362(Pt 2):481-90. doi: 10.1042/0264-6021:3620481. Biochem J. 2002. PMID: 11853558 Free PMC article.

4

Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.

Boudeau J, Deak M, Lawlor MA, Morrice NA, Alessi DR. Boudeau J, et al. Biochem J. 2003 Mar 15;370(Pt 3):849-57. doi: 10.1042/BJ20021813. Biochem J. 2003. PMID: 12489981 Free PMC article.

5

LKB1, a protein kinase regulating cell proliferation and polarity.

Boudeau J, Sapkota G, Alessi DR. Boudeau J, et al. FEBS Lett. 2003 Jul 3;546(1):159-65. doi: 10.1016/s0014-5793(03)00642-2. FEBS Lett. 2003. PMID: 12829253 Free article. Review.

6

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG. Hawley SA, et al. Among authors: boudeau j. J Biol. 2003;2(4):28. doi: 10.1186/1475-4924-2-28. Epub 2003 Sep 24. J Biol. 2003. PMID: 14511394 Free PMC article.

7

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR. Boudeau J, et al. EMBO J. 2003 Oct 1;22(19):5102-14. doi: 10.1093/emboj/cdg490. EMBO J. 2003. PMID: 14517248 Free PMC article.

8

Crystal structure of MO25 alpha in complex with the C terminus of the pseudo kinase STE20-related adaptor.

Milburn CC, Boudeau J, Deak M, Alessi DR, van Aalten DM. Milburn CC, et al. Among authors: boudeau j. Nat Struct Mol Biol. 2004 Feb;11(2):193-200. doi: 10.1038/nsmb716. Epub 2004 Jan 18. Nat Struct Mol Biol. 2004. PMID: 14730349

9

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR. Lizcano JM, et al. Among authors: boudeau j. EMBO J. 2004 Feb 25;23(4):833-43. doi: 10.1038/sj.emboj.7600110. Epub 2004 Feb 19. EMBO J. 2004. PMID: 14976552 Free PMC article.

10

Emerging roles of pseudokinases.

Boudeau J, Miranda-Saavedra D, Barton GJ, Alessi DR. Boudeau J, et al. Trends Cell Biol. 2006 Sep;16(9):443-52. doi: 10.1016/j.tcb.2006.07.003. Epub 2006 Aug 1. Trends Cell Biol. 2006. PMID: 16879967 Review.

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