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Page 1
In vitro activity of the new quinolone WCK 771 against staphylococci.
Jacobs MR, Bajaksouzian S, Windau A, Appelbaum PC, Patel MV, Gupte SV, Bhagwat SS, De Souza NJ, Khorakiwala HF. Jacobs MR, et al. Among authors: gupte sv. Antimicrob Agents Chemother. 2004 Sep;48(9):3338-42. doi: 10.1128/AAC.48.9.3338-3342.2004. Antimicrob Agents Chemother. 2004. PMID: 15328094 Free PMC article.
The anti-methicillin-resistant Staphylococcus aureus quinolone WCK 771 has potent activity against sequentially selected mutants, has a narrow mutant selection window against quinolone-resistant Staphylococcus aureus, and preferentially targets DNA gyrase.
Bhagwat SS, Mundkur LA, Gupte SV, Patel MV, Khorakiwala HF. Bhagwat SS, et al. Among authors: gupte sv. Antimicrob Agents Chemother. 2006 Nov;50(11):3568-79. doi: 10.1128/AAC.00641-06. Epub 2006 Aug 28. Antimicrob Agents Chemother. 2006. PMID: 16940059 Free PMC article.
Activity of the new quinolone WCK 771 against pneumococci.
Appelbaum PC, Pankuch GA, Bozdogan B, Lin G, Jacobs MR, Patel MV, Gupte SV, Jafri MA, De Souza NJ, Khorakiwala HF. Appelbaum PC, et al. Among authors: gupte sv. Clin Microbiol Infect. 2005 Jan;11(1):9-14. doi: 10.1111/j.1469-0691.2004.01017.x. Clin Microbiol Infect. 2005. PMID: 15649298 Free article.