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Mesenchymal stem cells home to injured tissues when co-infused with hematopoietic cells to treat a radiation-induced multi-organ failure syndrome.
Chapel A, Bertho JM, Bensidhoum M, Fouillard L, Young RG, Frick J, Demarquay C, Cuvelier F, Mathieu E, Trompier F, Dudoignon N, Germain C, Mazurier C, Aigueperse J, Borneman J, Gorin NC, Gourmelon P, Thierry D. Chapel A, et al. J Gene Med. 2003 Dec;5(12):1028-38. doi: 10.1002/jgm.452. J Gene Med. 2003. PMID: 14661178
Homing of in vitro expanded Stro-1- or Stro-1+ human mesenchymal stem cells into the NOD/SCID mouse and their role in supporting human CD34 cell engraftment.
Bensidhoum M, Chapel A, Francois S, Demarquay C, Mazurier C, Fouillard L, Bouchet S, Bertho JM, Gourmelon P, Aigueperse J, Charbord P, Gorin NC, Thierry D, Lopez M. Bensidhoum M, et al. Among authors: chapel a. Blood. 2004 May 1;103(9):3313-9. doi: 10.1182/blood-2003-04-1121. Epub 2004 Jan 8. Blood. 2004. PMID: 14715641 Free article.
Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: a study of their quantitative distribution after irradiation damage.
François S, Bensidhoum M, Mouiseddine M, Mazurier C, Allenet B, Semont A, Frick J, Saché A, Bouchet S, Thierry D, Gourmelon P, Gorin NC, Chapel A. François S, et al. Among authors: chapel a. Stem Cells. 2006 Apr;24(4):1020-9. doi: 10.1634/stemcells.2005-0260. Epub 2005 Dec 8. Stem Cells. 2006. PMID: 16339642
127 results