Tai HH - Search Results

1

Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase.

Cho H, Hamza A, Zhan CG, Tai HH. Cho H, et al. Among authors: tai hh. Arch Biochem Biophys. 2005 Jan 15;433(2):447-53. doi: 10.1016/j.abb.2004.09.036. Arch Biochem Biophys. 2005. PMID: 15581601

2

Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase.

Cho H, Oliveira MA, Tai HH. Cho H, et al. Among authors: tai hh. Arch Biochem Biophys. 2003 Nov 15;419(2):139-46. doi: 10.1016/j.abb.2003.09.019. Arch Biochem Biophys. 2003. PMID: 14592457

3

Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation.

Hamza A, Cho H, Tai HH, Zhan CG. Hamza A, et al. Among authors: tai hh. Bioorg Med Chem. 2005 Jul 15;13(14):4544-51. doi: 10.1016/j.bmc.2005.04.053. Bioorg Med Chem. 2005. PMID: 15908215

4

Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2.

Cho H, Huang L, Hamza A, Gao D, Zhan CG, Tai HH. Cho H, et al. Among authors: tai hh. Bioorg Med Chem. 2006 Oct 1;14(19):6486-91. doi: 10.1016/j.bmc.2006.06.030. Epub 2006 Jul 7. Bioorg Med Chem. 2006. PMID: 16828555

5

Thiazolidinediones as a novel class of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors.

Cho H, Tai HH. Cho H, et al. Among authors: tai hh. Arch Biochem Biophys. 2002 Sep 15;405(2):247-51. doi: 10.1016/s0003-9861(02)00352-1. Arch Biochem Biophys. 2002. PMID: 12220539

6

Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis.

Hamza A, Tong M, AbdulHameed MD, Liu J, Goren AC, Tai HH, Zhan CG. Hamza A, et al. Among authors: tai hh. J Phys Chem B. 2010 Apr 29;114(16):5605-16. doi: 10.1021/jp100668y. J Phys Chem B. 2010. PMID: 20369883 Free PMC article.

7

Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine.

Xue L, Ko MC, Tong M, Yang W, Hou S, Fang L, Liu J, Zheng F, Woods JH, Tai HH, Zhan CG. Xue L, et al. Among authors: tai hh. Mol Pharmacol. 2011 Feb;79(2):290-7. doi: 10.1124/mol.110.068494. Epub 2010 Oct 22. Mol Pharmacol. 2011. PMID: 20971807 Free PMC article.

8

Novel human mPGES-1 inhibitors identified through structure-based virtual screening.

Hamza A, Zhao X, Tong M, Tai HH, Zhan CG. Hamza A, et al. Among authors: tai hh. Bioorg Med Chem. 2011 Oct 15;19(20):6077-86. doi: 10.1016/j.bmc.2011.08.040. Epub 2011 Aug 25. Bioorg Med Chem. 2011. PMID: 21920764 Free PMC article.

9

Computational redesign of human butyrylcholinesterase for anticocaine medication.

Pan Y, Gao D, Yang W, Cho H, Yang G, Tai HH, Zhan CG. Pan Y, et al. Among authors: tai hh. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16656-61. doi: 10.1073/pnas.0507332102. Epub 2005 Nov 7. Proc Natl Acad Sci U S A. 2005. PMID: 16275916 Free PMC article.

10

Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation.

Gao D, Cho H, Yang W, Pan Y, Yang G, Tai HH, Zhan CG. Gao D, et al. Among authors: tai hh. Angew Chem Int Ed Engl. 2006 Jan 16;45(4):653-7. doi: 10.1002/anie.200503025. Angew Chem Int Ed Engl. 2006. PMID: 16355430 Free PMC article. No abstract available.

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