Kelly JA - Search Results

1

Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin".

Silvaggi NR, Josephine HR, Kuzin AP, Nagarajan R, Pratt RF, Kelly JA. Silvaggi NR, et al. Among authors: kelly ja. J Mol Biol. 2005 Jan 21;345(3):521-33. doi: 10.1016/j.jmb.2004.10.076. J Mol Biol. 2005. PMID: 15581896

2

Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.

McDonough MA, Anderson JW, Silvaggi NR, Pratt RF, Knox JR, Kelly JA. McDonough MA, et al. Among authors: kelly ja. J Mol Biol. 2002 Sep 6;322(1):111-22. doi: 10.1016/s0022-2836(02)00742-8. J Mol Biol. 2002. PMID: 12215418

3

The crystal structure of phosphonate-inhibited D-Ala-D-Ala peptidase reveals an analogue of a tetrahedral transition state.

Silvaggi NR, Anderson JW, Brinsmade SR, Pratt RF, Kelly JA. Silvaggi NR, et al. Among authors: kelly ja. Biochemistry. 2003 Feb 11;42(5):1199-208. doi: 10.1021/bi0268955. Biochemistry. 2003. PMID: 12564922

4

Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors.

Silvaggi NR, Kaur K, Adediran SA, Pratt RF, Kelly JA. Silvaggi NR, et al. Among authors: kelly ja. Biochemistry. 2004 Jun 8;43(22):7046-53. doi: 10.1021/bi049612c. Biochemistry. 2004. PMID: 15170342

5

The refined crystallographic structure of a DD-peptidase penicillin-target enzyme at 1.6 A resolution.

Kelly JA, Kuzin AP. Kelly JA, et al. J Mol Biol. 1995 Nov 24;254(2):223-36. doi: 10.1006/jmbi.1995.0613. J Mol Biol. 1995. PMID: 7490745

6

Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases.

Kuzin AP, Liu H, Kelly JA, Knox JR. Kuzin AP, et al. Among authors: kelly ja. Biochemistry. 1995 Jul 25;34(29):9532-40. doi: 10.1021/bi00029a030. Biochemistry. 1995. PMID: 7626623

7

X-ray studies of enzymes that interact with penicillins.

Kelly JA, Kuzin AP, Charlier P, Fonzé E. Kelly JA, et al. Cell Mol Life Sci. 1998 Apr;54(4):353-8. doi: 10.1007/s000180050163. Cell Mol Life Sci. 1998. PMID: 9614972 Free PMC article. Review.

8

Inactivation of bacterial DD-peptidase by beta-sultams.

Llinás A, Ahmed N, Cordaro M, Laws AP, Frère JM, Delmarcelle M, Silvaggi NR, Kelly JA, Page MI. Llinás A, et al. Among authors: kelly ja. Biochemistry. 2005 May 31;44(21):7738-46. doi: 10.1021/bi050110o. Biochemistry. 2005. PMID: 15909988 Free article.

9

A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis.

Lee W, McDonough MA, Kotra L, Li ZH, Silvaggi NR, Takeda Y, Kelly JA, Mobashery S. Lee W, et al. Among authors: kelly ja. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1427-31. doi: 10.1073/pnas.98.4.1427. Proc Natl Acad Sci U S A. 2001. PMID: 11171967 Free PMC article.

10

Crystallographic mapping of beta-lactams bound to a D-alanyl-D-alanine peptidase target enzyme.

Kelly JA, Knox JR, Zhao H, Frère JM, Ghaysen JM. Kelly JA, et al. J Mol Biol. 1989 Sep 20;209(2):281-95. doi: 10.1016/0022-2836(89)90277-5. J Mol Biol. 1989. PMID: 2585485 Free article.

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