Wilcock DM - Search Results

1

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage.

Wilcock DM, Rojiani A, Rosenthal A, Subbarao S, Freeman MJ, Gordon MN, Morgan D. Wilcock DM, et al. J Neuroinflammation. 2004 Dec 8;1(1):24. doi: 10.1186/1742-2094-1-24. J Neuroinflammation. 2004. PMID: 15588287 Free PMC article.

2

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. Morgan D, et al. Among authors: wilcock d. Nature. 2000 Dec 21-28;408(6815):982-5. doi: 10.1038/35050116. Nature. 2000. PMID: 11140686

3

Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice.

DiCarlo G, Wilcock D, Henderson D, Gordon M, Morgan D. DiCarlo G, et al. Neurobiol Aging. 2001 Nov-Dec;22(6):1007-12. doi: 10.1016/s0197-4580(01)00292-5. Neurobiol Aging. 2001. PMID: 11755009

4

Number of Abeta inoculations in APP+PS1 transgenic mice influences antibody titers, microglial activation, and congophilic plaque levels.

Wilcock DM, Gordon MN, Ugen KE, Gottschall PE, DiCarlo G, Dickey C, Boyett KW, Jantzen PT, Connor KE, Melachrino J, Hardy J, Morgan D. Wilcock DM, et al. DNA Cell Biol. 2001 Nov;20(11):731-6. doi: 10.1089/10445490152717596. DNA Cell Biol. 2001. PMID: 11788051

5

Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory.

Arendash GW, Gordon MN, Diamond DM, Austin LA, Hatcher JM, Jantzen P, DiCarlo G, Wilcock D, Morgan D. Arendash GW, et al. Among authors: wilcock d. DNA Cell Biol. 2001 Nov;20(11):737-44. doi: 10.1089/10445490152717604. DNA Cell Biol. 2001. PMID: 11788052

6

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse.

Gordon MN, Holcomb LA, Jantzen PT, DiCarlo G, Wilcock D, Boyett KW, Connor K, Melachrino J, O'Callaghan JP, Morgan D. Gordon MN, et al. Exp Neurol. 2002 Feb;173(2):183-95. doi: 10.1006/exnr.2001.7754. Exp Neurol. 2002. PMID: 11822882

7

Increased fibrillar beta-amyloid in response to human clq injections into hippocampus and cortex of APP+PS1 transgenic mice.

Boyett KW, DiCarlo G, Jantzen PT, Jackson J, O'Leary C, Wilcock D, Morgan D, Gordon MN. Boyett KW, et al. Neurochem Res. 2003 Jan;28(1):83-93. doi: 10.1023/a:1021600212829. Neurochem Res. 2003. PMID: 12587666

8

Intracranially administered anti-Abeta antibodies reduce beta-amyloid deposition by mechanisms both independent of and associated with microglial activation.

Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen KE, Gordon MN, Morgan D. Wilcock DM, et al. J Neurosci. 2003 May 1;23(9):3745-51. doi: 10.1523/JNEUROSCI.23-09-03745.2003. J Neurosci. 2003. PMID: 12736345 Free PMC article.

9

Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration.

Wilcock DM, Munireddy SK, Rosenthal A, Ugen KE, Gordon MN, Morgan D. Wilcock DM, et al. Neurobiol Dis. 2004 Feb;15(1):11-20. doi: 10.1016/j.nbd.2003.09.015. Neurobiol Dis. 2004. PMID: 14751766

10

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

Wilcock DM, Rojiani A, Rosenthal A, Levkowitz G, Subbarao S, Alamed J, Wilson D, Wilson N, Freeman MJ, Gordon MN, Morgan D. Wilcock DM, et al. J Neurosci. 2004 Jul 7;24(27):6144-51. doi: 10.1523/JNEUROSCI.1090-04.2004. J Neurosci. 2004. PMID: 15240806 Free PMC article.

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