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Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway.
Grace MJ, Lee S, Bradshaw S, Chapman J, Spond J, Cox S, Delorenzo M, Brassard D, Wylie D, Cannon-Carlson S, Cullen C, Indelicato S, Voloch M, Bordens R. Grace MJ, et al. Among authors: brassard d. J Biol Chem. 2005 Feb 25;280(8):6327-36. doi: 10.1074/jbc.M412134200. Epub 2004 Dec 13. J Biol Chem. 2005. PMID: 15596441 Free article.
Structural and biologic characterization of pegylated recombinant IFN-alpha2b.
Grace M, Youngster S, Gitlin G, Sydor W, Xie L, Westreich L, Jacobs S, Brassard D, Bausch J, Bordens R. Grace M, et al. Among authors: brassard d. J Interferon Cytokine Res. 2001 Dec;21(12):1103-15. doi: 10.1089/107999001317205240. J Interferon Cytokine Res. 2001. PMID: 11798469
Integrin alpha(v)beta(3)-mediated activation of apoptosis.
Brassard DL, Maxwell E, Malkowski M, Nagabhushan TL, Kumar CC, Armstrong L. Brassard DL, et al. Exp Cell Res. 1999 Aug 25;251(1):33-45. doi: 10.1006/excr.1999.4559. Exp Cell Res. 1999. PMID: 10438569
70 results