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Page 1
Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor.
Kadono S, Sakamoto A, Kikuchi Y, Oh-Eda M, Yabuta N, Yoshihashi K, Kitazawa T, Suzuki T, Koga T, Hattori K, Shiraishi T, Haramura M, Kodama H, Ono Y, Esaki T, Sato H, Watanabe Y, Itoh S, Ohta M, Kozono T. Kadono S, et al. Among authors: kodama h. Biochem Biophys Res Commun. 2005 Jan 28;326(4):859-65. doi: 10.1016/j.bbrc.2004.11.108. Biochem Biophys Res Commun. 2005. PMID: 15607748
Structure-based design of P3 moieties in the peptide mimetic factor VIIa inhibitor.
Kadono S, Sakamoto A, Kikuchi Y, Oh-eda M, Yabuta N, Yoshihashi K, Kitazawa T, Suzuki T, Koga T, Hattori K, Shiraishi T, Haramura M, Kodama H, Ono Y, Esaki T, Sato H, Watanabe Y, Itoh S, Ohta M, Kozono T. Kadono S, et al. Among authors: kodama h. Biochem Biophys Res Commun. 2005 Feb 11;327(2):589-96. doi: 10.1016/j.bbrc.2004.12.042. Biochem Biophys Res Commun. 2005. PMID: 15629154
Structure of human factor VIIa/tissue factor in complex with a peptide-mimetic inhibitor: high selectivity against thrombin by introducing two charged groups in P2 and P4.
Kadono S, Sakamoto A, Kikuchi Y, Oh-Eda M, Yabuta N, Koga T, Hattori K, Shiraishi T, Haramura M, Kodama H, Ono Y, Esaki T, Sato H, Watanabe Y, Itoh S, Ohta M, Kozono T. Kadono S, et al. Among authors: kodama h. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Feb 1;61(Pt 2):169-73. doi: 10.1107/S1744309105000047. Epub 2005 Jan 20. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005. PMID: 16510984 Free PMC article.
Factor VIIa inhibitors: target hopping in the serine protease family using X-ray structure determination.
Shiraishi T, Kadono S, Haramura M, Kodama H, Ono Y, Iikura H, Esaki T, Koga T, Hattori K, Watanabe Y, Sakamoto A, Yoshihashi K, Kitazawa T, Esaki K, Ohta M, Sato H, Kozono T. Shiraishi T, et al. Among authors: kodama h. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4533-7. doi: 10.1016/j.bmcl.2008.07.044. Epub 2008 Jul 16. Bioorg Med Chem Lett. 2008. PMID: 18674905
Design and synthesis of peptidomimetic factor VIIa inhibitors.
Shiraishi T, Kadono S, Haramura M, Kodama H, Ono Y, Iikura H, Esaki T, Koga T, Hattori K, Watanabe Y, Sakamoto A, Yoshihashi K, Kitazawa T, Esaki K, Ohta M, Sato H, Kozono T. Shiraishi T, et al. Among authors: kodama h. Chem Pharm Bull (Tokyo). 2010 Jan;58(1):38-44. doi: 10.1248/cpb.58.38. Chem Pharm Bull (Tokyo). 2010. PMID: 20045964 Free article.
Efficacy of subsequent treatment for unresectable locally-advanced non-small cell lung cancer after relapse of concurrent chemoradiotherapy with durvalumab consolidation therapy: A single-center retrospective study.
Nishibori Y, Kenmotsu H, Ando K, Tonsho A, Matsuda S, Morita M, Sekikawa M, Doshita K, Morikawa N, Miura K, Kodama H, Yabe M, Iida Y, Mamesaya N, Kobayashi H, Ko R, Wakuda K, Ono A, Naito T, Murakami H, Harada H, Takahashi T. Nishibori Y, et al. Among authors: kodama h. Cancer Treat Res Commun. 2024 Nov 8;41:100849. doi: 10.1016/j.ctarc.2024.100849. Online ahead of print. Cancer Treat Res Commun. 2024. PMID: 39536390 Free article.
Comparison of efficacy of gefitinib and osimertinib for untreated EGFR mutation-positive non-small-cell lung cancer in patients with poor performance status.
Nakashima K, Kodama H, Murakami H, Takahashi T, Kawakado K, Yanagawa T, Kitani K, Hottta T, Abe M, Hamai K, Tanimoto T, Ishikawa N, Tamura T, Kuyama S, Isobe T, Tsubata Y. Nakashima K, et al. Among authors: kodama h. Respir Investig. 2024 Oct 3;62(6):1137-1141. doi: 10.1016/j.resinv.2024.09.010. Online ahead of print. Respir Investig. 2024. PMID: 39366122 Free article.
1,434 results