O'Shea JJ - Search Results

1

CXCL12 signaling is independent of Jak2 and Jak3.

Moriguchi M, Hissong BD, Gadina M, Yamaoka K, Tiffany HL, Murphy PM, Candotti F, O'Shea JJ. Moriguchi M, et al. J Biol Chem. 2005 Apr 29;280(17):17408-14. doi: 10.1074/jbc.M414219200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611059 Free article.

2

Expression of the human epidermal growth factor receptor in a murine T-cell hybridoma. A transmembrane protein tyrosine kinase can synergize with the T-cell antigen receptor.

Kennedy IC, June CH, O'Shea JJ. Kennedy IC, et al. J Biol Chem. 1992 Mar 5;267(7):4924-9. J Biol Chem. 1992. PMID: 1537871 Free article.

3

Tyrosine kinase-regulated and inositol phosphate-independent Ca2+ elevation and mobilization in T cells.

Niklinska BB, Yamada H, O'Shea JJ, June CH, Ashwell JD. Niklinska BB, et al. J Biol Chem. 1992 Apr 5;267(10):7154-9. J Biol Chem. 1992. PMID: 1551921 Free article.

4

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

Russell SM, Tayebi N, Nakajima H, Riedy MC, Roberts JL, Aman MJ, Migone TS, Noguchi M, Markert ML, Buckley RH, O'Shea JJ, Leonard WJ. Russell SM, et al. Science. 1995 Nov 3;270(5237):797-800. doi: 10.1126/science.270.5237.797. Science. 1995. PMID: 7481768

5

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases.

Johnston JA, Wang LM, Hanson EP, Sun XJ, White MF, Oakes SA, Pierce JH, O'Shea JJ. Johnston JA, et al. J Biol Chem. 1995 Dec 1;270(48):28527-30. doi: 10.1074/jbc.270.48.28527. J Biol Chem. 1995. PMID: 7499365 Free article.

6

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID).

Macchi P, Villa A, Giliani S, Sacco MG, Frattini A, Porta F, Ugazio AG, Johnston JA, Candotti F, O'Shea JJ, et al. Macchi P, et al. Nature. 1995 Sep 7;377(6544):65-8. doi: 10.1038/377065a0. Nature. 1995. PMID: 7659163

7

Activation of JAK3, but not JAK1, is critical to interleukin-4 (IL4) stimulated proliferation and requires a membrane-proximal region of IL4 receptor alpha.

Malabarba MG, Kirken RA, Rui H, Koettnitz K, Kawamura M, O'Shea JJ, Kalthoff FS, Farrar WL. Malabarba MG, et al. J Biol Chem. 1995 Apr 21;270(16):9630-7. doi: 10.1074/jbc.270.16.9630. J Biol Chem. 1995. PMID: 7721895 Free article.

8

Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2.

Tortolani PJ, Johnston JA, Bacon CM, McVicar DW, Shimosaka A, Linnekin D, Longo DL, O'Shea JJ. Tortolani PJ, et al. Blood. 1995 Jun 15;85(12):3444-51. Blood. 1995. PMID: 7780132 Free article.

9

Retroviral-mediated gene correction for X-linked severe combined immunodeficiency.

Candotti F, Johnston JA, Puck JM, Sugamura K, O'Shea JJ, Blaese RM. Candotti F, et al. Blood. 1996 Apr 15;87(8):3097-102. Blood. 1996. PMID: 8605322 Free article.

10

In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction.

Candotti F, Oakes SA, Johnston JA, Notarangelo LD, O'Shea JJ, Blaese RM. Candotti F, et al. J Exp Med. 1996 Jun 1;183(6):2687-92. doi: 10.1084/jem.183.6.2687. J Exp Med. 1996. PMID: 8676091 Free PMC article.

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