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Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.
Patel JB, Huynh CK, Handratta VD, Gediya LK, Brodie AM, Goloubeva OG, Clement OO, Nanne IP, Soprano DR, Njar VC. Patel JB, et al. Among authors: clement oo. J Med Chem. 2004 Dec 30;47(27):6716-29. doi: 10.1021/jm0401457. J Med Chem. 2004. PMID: 15615521