Abbott DW - Search Results

1

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO.

Abbott DW, Wilkins A, Asara JM, Cantley LC. Abbott DW, et al. Curr Biol. 2004 Dec 29;14(24):2217-27. doi: 10.1016/j.cub.2004.12.032. Curr Biol. 2004. PMID: 15620648 Free article.

2

A rapid method for determining protein kinase phosphorylation specificity.

Hutti JE, Jarrell ET, Chang JD, Abbott DW, Storz P, Toker A, Cantley LC, Turk BE. Hutti JE, et al. Among authors: abbott dw. Nat Methods. 2004 Oct;1(1):27-9. doi: 10.1038/nmeth708. Nat Methods. 2004. PMID: 15782149

3

The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape.

Kang CM, Abbott DW, Park ST, Dascher CC, Cantley LC, Husson RN. Kang CM, et al. Among authors: abbott dw. Genes Dev. 2005 Jul 15;19(14):1692-704. doi: 10.1101/gad.1311105. Epub 2005 Jun 28. Genes Dev. 2005. PMID: 15985609 Free PMC article.

4

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.

Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC. Abbott DW, et al. Mol Cell Biol. 2007 Sep;27(17):6012-25. doi: 10.1128/MCB.00270-07. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562858 Free PMC article.

5

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway.

Hutti JE, Turk BE, Asara JM, Ma A, Cantley LC, Abbott DW. Hutti JE, et al. Among authors: abbott dw. Mol Cell Biol. 2007 Nov;27(21):7451-61. doi: 10.1128/MCB.01101-07. Epub 2007 Aug 20. Mol Cell Biol. 2007. PMID: 17709380 Free PMC article.

6

NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.

Yang Y, Yin C, Pandey A, Abbott D, Sassetti C, Kelliher MA. Yang Y, et al. J Biol Chem. 2007 Dec 14;282(50):36223-9. doi: 10.1074/jbc.M703079200. Epub 2007 Oct 18. J Biol Chem. 2007. PMID: 17947236 Free article.

7

MEKK4 sequesters RIP2 to dictate NOD2 signal specificity.

Clark NM, Marinis JM, Cobb BA, Abbott DW. Clark NM, et al. Among authors: abbott dw. Curr Biol. 2008 Sep 23;18(18):1402-8. doi: 10.1016/j.cub.2008.07.084. Epub 2008 Sep 4. Curr Biol. 2008. PMID: 18775659 Free PMC article.

8

Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation.

Hutti JE, Shen RR, Abbott DW, Zhou AY, Sprott KM, Asara JM, Hahn WC, Cantley LC. Hutti JE, et al. Among authors: abbott dw. Mol Cell. 2009 May 14;34(4):461-72. doi: 10.1016/j.molcel.2009.04.031. Mol Cell. 2009. PMID: 19481526 Free PMC article.

9

ITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathways.

Tao M, Scacheri PC, Marinis JM, Harhaj EW, Matesic LE, Abbott DW. Tao M, et al. Among authors: abbott dw. Curr Biol. 2009 Aug 11;19(15):1255-63. doi: 10.1016/j.cub.2009.06.038. Epub 2009 Jul 9. Curr Biol. 2009. PMID: 19592251 Free PMC article.

10

Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.

Tigno-Aranjuez JT, Asara JM, Abbott DW. Tigno-Aranjuez JT, et al. Among authors: abbott dw. Genes Dev. 2010 Dec 1;24(23):2666-77. doi: 10.1101/gad.1964410. Genes Dev. 2010. PMID: 21123652 Free PMC article.

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