Kosmopoulou MN - Search Results

1

Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies.

Chrysina ED, Kosmopoulou MN, Kardakaris R, Bischler N, Leonidas DD, Kannan T, Loganathan D, Oikonomakos NG. Chrysina ED, et al. Among authors: kosmopoulou mn. Bioorg Med Chem. 2005 Feb 1;13(3):765-72. doi: 10.1016/j.bmc.2004.10.040. Bioorg Med Chem. 2005. PMID: 15653344

2

Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution.

Oikonomakos NG, Chrysina ED, Kosmopoulou MN, Leonidas DD. Oikonomakos NG, et al. Among authors: kosmopoulou mn. Biochim Biophys Acta. 2003 Apr 11;1647(1-2):325-32. doi: 10.1016/s1570-9639(03)00085-2. Biochim Biophys Acta. 2003. PMID: 12686153

3

Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex.

Kosmopoulou MN, Leonidas DD, Chrysina ED, Bischler N, Eisenbrand G, Sakarellos CE, Pauptit R, Oikonomakos NG. Kosmopoulou MN, et al. Eur J Biochem. 2004 Jun;271(11):2280-90. doi: 10.1111/j.1432-1033.2004.04173.x. Eur J Biochem. 2004. PMID: 15153119 Free article.

4

Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.

Chrysina ED, Kosmopoulou MN, Tiraidis C, Kardakaris R, Bischler N, Leonidas DD, Hadady Z, Somsak L, Docsa T, Gergely P, Oikonomakos NG. Chrysina ED, et al. Among authors: kosmopoulou mn. Protein Sci. 2005 Apr;14(4):873-88. doi: 10.1110/ps.041216105. Epub 2005 Mar 1. Protein Sci. 2005. PMID: 15741340 Free PMC article.

5

Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.

Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E. Oikonomakos NG, et al. Among authors: kosmopoulou mn. Protein Sci. 2005 Jul;14(7):1760-71. doi: 10.1110/ps.051432405. Protein Sci. 2005. PMID: 15987904 Free PMC article.

6

Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase.

Anagnostou E, Kosmopoulou MN, Chrysina ED, Leonidas DD, Hadjiloi T, Tiraidis C, Zographos SE, Györgydeák Z, Somsák L, Docsa T, Gergely P, Kolisis FN, Oikonomakos NG. Anagnostou E, et al. Among authors: kosmopoulou mn. Bioorg Med Chem. 2006 Jan 1;14(1):181-9. doi: 10.1016/j.bmc.2005.08.010. Epub 2005 Oct 4. Bioorg Med Chem. 2006. PMID: 16213146

7

Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site.

Hampson LJ, Arden C, Agius L, Ganotidis M, Kosmopoulou MN, Tiraidis C, Elemes Y, Sakarellos C, Leonidas DD, Oikonomakos NG. Hampson LJ, et al. Among authors: kosmopoulou mn. Bioorg Med Chem. 2006 Dec 1;14(23):7835-45. doi: 10.1016/j.bmc.2006.07.060. Bioorg Med Chem. 2006. PMID: 16908161

8

N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.

Nagy V, Felföldi N, Kónya B, Praly JP, Docsa T, Gergely P, Chrysina ED, Tiraidis C, Kosmopoulou MN, Alexacou KM, Konstantakaki M, Leonidas DD, Zographos SE, Oikonomakos NG, Kozmon S, Tvaroška I, Somsák L. Nagy V, et al. Among authors: kosmopoulou mn. Bioorg Med Chem. 2012 Mar 1;20(5):1801-16. doi: 10.1016/j.bmc.2011.12.059. Epub 2012 Jan 20. Bioorg Med Chem. 2012. PMID: 22325154

9

Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.

Oikonomakos NG, Kosmopoulou M, Zographos SE, Leonidas DD, Chrysina ED, Somsák L, Nagy V, Praly JP, Docsa T, Tóth B, Gergely P. Oikonomakos NG, et al. Eur J Biochem. 2002 Mar;269(6):1684-96. doi: 10.1046/j.1432-1327.2002.02813.x. Eur J Biochem. 2002. PMID: 11895439 Free article.

10

Crystallization and preliminary X-ray crystallographic analysis of Sclerotium rolfsii lectin.

Leonidas DD, Swamy BM, Bhat AG, Inamdar SR, Kosmopoulou MN, Chrysina ED, Oikonomakos NG. Leonidas DD, et al. Among authors: kosmopoulou mn. Acta Crystallogr D Biol Crystallogr. 2003 Feb;59(Pt 2):363-5. doi: 10.1107/s0907444902021121. Epub 2003 Jan 23. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12554954

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