Oikonomakos NG - Search Results

1

Binding of beta-D-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies.

Chrysina ED, Kosmopoulou MN, Kardakaris R, Bischler N, Leonidas DD, Kannan T, Loganathan D, Oikonomakos NG. Chrysina ED, et al. Among authors: oikonomakos ng. Bioorg Med Chem. 2005 Feb 1;13(3):765-72. doi: 10.1016/j.bmc.2004.10.040. Bioorg Med Chem. 2005. PMID: 15653344

2

Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies.

Oikonomakos NG, Kosmopoulou M, Zographos SE, Leonidas DD, Chrysina ED, Somsák L, Nagy V, Praly JP, Docsa T, Tóth B, Gergely P. Oikonomakos NG, et al. Eur J Biochem. 2002 Mar;269(6):1684-96. doi: 10.1046/j.1432-1327.2002.02813.x. Eur J Biochem. 2002. PMID: 11895439 Free article.

3

Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution.

Oikonomakos NG, Chrysina ED, Kosmopoulou MN, Leonidas DD. Oikonomakos NG, et al. Biochim Biophys Acta. 2003 Apr 11;1647(1-2):325-32. doi: 10.1016/s1570-9639(03)00085-2. Biochim Biophys Acta. 2003. PMID: 12686153

4

The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: kinetic and crystallographic studies.

Pinotsis N, Leonidas DD, Chrysina ED, Oikonomakos NG, Mavridis IM. Pinotsis N, et al. Among authors: oikonomakos ng. Protein Sci. 2003 Sep;12(9):1914-24. doi: 10.1110/ps.03149503. Protein Sci. 2003. PMID: 12930991 Free PMC article.

5

Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex.

Kosmopoulou MN, Leonidas DD, Chrysina ED, Bischler N, Eisenbrand G, Sakarellos CE, Pauptit R, Oikonomakos NG. Kosmopoulou MN, et al. Among authors: oikonomakos ng. Eur J Biochem. 2004 Jun;271(11):2280-90. doi: 10.1111/j.1432-1033.2004.04173.x. Eur J Biochem. 2004. PMID: 15153119 Free article.

6

Kinetic and crystallographic studies on 2-(beta-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site.

Chrysina ED, Kosmopoulou MN, Tiraidis C, Kardakaris R, Bischler N, Leonidas DD, Hadady Z, Somsak L, Docsa T, Gergely P, Oikonomakos NG. Chrysina ED, et al. Among authors: oikonomakos ng. Protein Sci. 2005 Apr;14(4):873-88. doi: 10.1110/ps.041216105. Epub 2005 Mar 1. Protein Sci. 2005. PMID: 15741340 Free PMC article.

7

Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs.

Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E. Oikonomakos NG, et al. Protein Sci. 2005 Jul;14(7):1760-71. doi: 10.1110/ps.051432405. Protein Sci. 2005. PMID: 15987904 Free PMC article.

8

Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase.

Anagnostou E, Kosmopoulou MN, Chrysina ED, Leonidas DD, Hadjiloi T, Tiraidis C, Zographos SE, Györgydeák Z, Somsák L, Docsa T, Gergely P, Kolisis FN, Oikonomakos NG. Anagnostou E, et al. Among authors: oikonomakos ng. Bioorg Med Chem. 2006 Jan 1;14(1):181-9. doi: 10.1016/j.bmc.2005.08.010. Epub 2005 Oct 4. Bioorg Med Chem. 2006. PMID: 16213146

9

Binding of oxalyl derivatives of beta-d-glucopyranosylamine to muscle glycogen phosphorylase b.

Hadjiloi T, Tiraidis C, Chrysina ED, Leonidas DD, Oikonomakos NG, Tsipos P, Gimisis T. Hadjiloi T, et al. Among authors: oikonomakos ng. Bioorg Med Chem. 2006 Jun 1;14(11):3872-82. doi: 10.1016/j.bmc.2006.01.045. Epub 2006 Feb 7. Bioorg Med Chem. 2006. PMID: 16464598

10

Crystallographic studies on N-azidoacetyl-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine.

Petsalakis EI, Chrysina ED, Tiraidis C, Hadjiloi T, Leonidas DD, Oikonomakos NG, Aich U, Varghese B, Loganathan D. Petsalakis EI, et al. Among authors: oikonomakos ng. Bioorg Med Chem. 2006 Aug 1;14(15):5316-24. doi: 10.1016/j.bmc.2006.03.044. Epub 2006 Apr 17. Bioorg Med Chem. 2006. PMID: 16616506

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