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Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.
Rutanen J, Rissanen TT, Markkanen JE, Gruchala M, Silvennoinen P, Kivelä A, Hedman A, Hedman M, Heikura T, Ordén MR, Stacker SA, Achen MG, Hartikainen J, Ylä-Herttuala S. Rutanen J, et al. Among authors: kivela a. Circulation. 2004 Mar 2;109(8):1029-35. doi: 10.1161/01.CIR.0000115519.03688.A2. Epub 2004 Feb 16. Circulation. 2004. PMID: 14967735
Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms.
Lähteenvuo JE, Lähteenvuo MT, Kivelä A, Rosenlew C, Falkevall A, Klar J, Heikura T, Rissanen TT, Vähäkangas E, Korpisalo P, Enholm B, Carmeliet P, Alitalo K, Eriksson U, Ylä-Herttuala S. Lähteenvuo JE, et al. Among authors: kivela a. Circulation. 2009 Feb 17;119(6):845-56. doi: 10.1161/CIRCULATIONAHA.108.816454. Epub 2009 Feb 2. Circulation. 2009. PMID: 19188502
Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT).
Hedman M, Hartikainen J, Syvänne M, Stjernvall J, Hedman A, Kivelä A, Vanninen E, Mussalo H, Kauppila E, Simula S, Närvänen O, Rantala A, Peuhkurinen K, Nieminen MS, Laakso M, Ylä-Herttuala S. Hedman M, et al. Among authors: kivela a. Circulation. 2003 Jun 3;107(21):2677-83. doi: 10.1161/01.CIR.0000070540.80780.92. Epub 2003 May 12. Circulation. 2003. PMID: 12742981 Clinical Trial.
Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up.
Hartikainen J, Hassinen I, Hedman A, Kivelä A, Saraste A, Knuuti J, Husso M, Mussalo H, Hedman M, Rissanen TT, Toivanen P, Heikura T, Witztum JL, Tsimikas S, Ylä-Herttuala S. Hartikainen J, et al. Among authors: kivela a. Eur Heart J. 2017 Sep 1;38(33):2547-2555. doi: 10.1093/eurheartj/ehx352. Eur Heart J. 2017. PMID: 28903476 Free PMC article. Clinical Trial.
133 results