Sternweis PC - Search Results

1

Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.

Chen Z, Singer WD, Sternweis PC, Sprang SR. Chen Z, et al. Among authors: sternweis pc. Nat Struct Mol Biol. 2005 Feb;12(2):191-7. doi: 10.1038/nsmb888. Epub 2005 Jan 16. Nat Struct Mol Biol. 2005. PMID: 15665872

2

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF.

Chen Z, Singer WD, Wells CD, Sprang SR, Sternweis PC. Chen Z, et al. Among authors: sternweis pc. J Biol Chem. 2003 Mar 14;278(11):9912-9. doi: 10.1074/jbc.M212695200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525488 Free article.

3

Regulation of Rho guanine nucleotide exchange factors by G proteins.

Sternweis PC, Carter AM, Chen Z, Danesh SM, Hsiung YF, Singer WD. Sternweis PC, et al. Adv Protein Chem. 2007;74:189-228. doi: 10.1016/S0065-3233(07)74006-8. Adv Protein Chem. 2007. PMID: 17854659 Review.

4

Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.

Chen Z, Singer WD, Danesh SM, Sternweis PC, Sprang SR. Chen Z, et al. Among authors: sternweis pc. Structure. 2008 Oct 8;16(10):1532-43. doi: 10.1016/j.str.2008.07.009. Structure. 2008. PMID: 18940608 Free PMC article.

5

Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.

Chen Z, Medina F, Liu MY, Thomas C, Sprang SR, Sternweis PC. Chen Z, et al. Among authors: sternweis pc. J Biol Chem. 2010 Jul 2;285(27):21070-81. doi: 10.1074/jbc.M110.122549. Epub 2010 Apr 29. J Biol Chem. 2010. PMID: 20430886 Free PMC article.

6

Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF.

Chen Z, Guo L, Sprang SR, Sternweis PC. Chen Z, et al. Among authors: sternweis pc. Protein Sci. 2011 Jan;20(1):107-17. doi: 10.1002/pro.542. Protein Sci. 2011. PMID: 21064165 Free PMC article.

7

Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain.

Chen Z, Guo L, Hadas J, Gutowski S, Sprang SR, Sternweis PC. Chen Z, et al. Among authors: sternweis pc. J Biol Chem. 2012 Jul 20;287(30):25490-500. doi: 10.1074/jbc.M111.333716. Epub 2012 Jun 1. J Biol Chem. 2012. PMID: 22661716 Free PMC article.

8

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.

Kozasa T, Jiang X, Hart MJ, Sternweis PM, Singer WD, Gilman AG, Bollag G, Sternweis PC. Kozasa T, et al. Among authors: sternweis pc, sternweis pm. Science. 1998 Jun 26;280(5372):2109-11. doi: 10.1126/science.280.5372.2109. Science. 1998. PMID: 9641915

9

Structure of the rgRGS domain of p115RhoGEF.

Chen Z, Wells CD, Sternweis PC, Sprang SR. Chen Z, et al. Among authors: sternweis pc. Nat Struct Biol. 2001 Sep;8(9):805-9. doi: 10.1038/nsb0901-805. Nat Struct Biol. 2001. PMID: 11524686

10

Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins.

Medina F, Carter AM, Dada O, Gutowski S, Hadas J, Chen Z, Sternweis PC. Medina F, et al. Among authors: sternweis pc. J Biol Chem. 2013 Apr 19;288(16):11325-33. doi: 10.1074/jbc.M113.450056. Epub 2013 Mar 14. J Biol Chem. 2013. PMID: 23493395 Free PMC article.

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