Maeda S - Search Results

1

IKK-beta links inflammation to obesity-induced insulin resistance.

Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. Arkan MC, et al. Among authors: maeda s. Nat Med. 2005 Feb;11(2):191-8. doi: 10.1038/nm1185. Epub 2005 Jan 30. Nat Med. 2005. PMID: 15685170

2

IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis.

Sil AK, Maeda S, Sano Y, Roop DR, Karin M. Sil AK, et al. Among authors: maeda s. Nature. 2004 Apr 8;428(6983):660-4. doi: 10.1038/nature02421. Nature. 2004. PMID: 15071597

3

I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss.

Ruocco MG, Maeda S, Park JM, Lawrence T, Hsu LC, Cao Y, Schett G, Wagner EF, Karin M. Ruocco MG, et al. Among authors: maeda s. J Exp Med. 2005 May 16;201(10):1677-87. doi: 10.1084/jem.20042081. J Exp Med. 2005. PMID: 15897281 Free PMC article.

4

IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha.

Maeda S, Chang L, Li ZW, Luo JL, Leffert H, Karin M. Maeda S, et al. Immunity. 2003 Nov;19(5):725-37. doi: 10.1016/s1074-7613(03)00301-7. Immunity. 2003. PMID: 14614859 Free article.

5

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

Hsu LC, Park JM, Zhang K, Luo JL, Maeda S, Kaufman RJ, Eckmann L, Guiney DG, Karin M. Hsu LC, et al. Among authors: maeda s. Nature. 2004 Mar 18;428(6980):341-5. doi: 10.1038/nature02405. Nature. 2004. PMID: 15029200 Free article.

6

Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression.

Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Luo JL, et al. Among authors: maeda s. Cancer Cell. 2004 Sep;6(3):297-305. doi: 10.1016/j.ccr.2004.08.012. Cancer Cell. 2004. PMID: 15380520 Free article.

7

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis.

Maeda S, Kamata H, Luo JL, Leffert H, Karin M. Maeda S, et al. Cell. 2005 Jul 1;121(7):977-90. doi: 10.1016/j.cell.2005.04.014. Cell. 2005. PMID: 15989949 Free article.

8

Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation.

Sakurai T, Maeda S, Chang L, Karin M. Sakurai T, et al. Among authors: maeda s. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10544-51. doi: 10.1073/pnas.0603499103. Epub 2006 Jun 28. Proc Natl Acad Sci U S A. 2006. PMID: 16807293 Free PMC article.

9

Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis.

Sakurai T, He G, Matsuzawa A, Yu GY, Maeda S, Hardiman G, Karin M. Sakurai T, et al. Among authors: maeda s. Cancer Cell. 2008 Aug 12;14(2):156-65. doi: 10.1016/j.ccr.2008.06.016. Cancer Cell. 2008. PMID: 18691550 Free PMC article.

10

Targeted deletion of hepatocyte Ikkbeta confers growth advantages.

Koch KS, Maeda S, He G, Karin M, Leffert HL. Koch KS, et al. Among authors: maeda s. Biochem Biophys Res Commun. 2009 Mar 6;380(2):349-54. doi: 10.1016/j.bbrc.2009.01.085. Epub 2009 Jan 24. Biochem Biophys Res Commun. 2009. PMID: 19171122 Free PMC article.

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