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15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure.
Leonard MO, Hannan K, Burne MJ, Lappin DW, Doran P, Coleman P, Stenson C, Taylor CT, Daniels F, Godson C, Petasis NA, Rabb H, Brady HR. Leonard MO, et al. Among authors: brady hr. J Am Soc Nephrol. 2002 Jun;13(6):1657-62. doi: 10.1097/01.asn.0000015795.74094.91. J Am Soc Nephrol. 2002. PMID: 12039996
IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.
Murphy M, Docherty NG, Griffin B, Howlin J, McArdle E, McMahon R, Schmid H, Kretzler M, Droguett A, Mezzano S, Brady HR, Furlong F, Godson C, Martin F. Murphy M, et al. Among authors: brady hr. J Am Soc Nephrol. 2008 Sep;19(9):1672-80. doi: 10.1681/ASN.2007101080. Epub 2008 May 28. J Am Soc Nephrol. 2008. PMID: 18508967 Free PMC article.
Lipoxins: novel anti-inflammatory therapeutics?
Godson C, Brady HR. Godson C, et al. Among authors: brady hr. Curr Opin Investig Drugs. 2000 Nov;1(3):380-5. Curr Opin Investig Drugs. 2000. PMID: 11249723 Review.
151 results