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5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
Mai A, Artico M, Ragno R, Sbardella G, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, Maga G, La Colla P. Mai A, et al. Among authors: sbardella g. Bioorg Med Chem. 2005 Mar 15;13(6):2065-77. doi: 10.1016/j.bmc.2005.01.005. Bioorg Med Chem. 2005. PMID: 15727860
Nitroquinolones with broad-spectrum antimycobacterial activity in vitro.
Artico M, Mai A, Sbardella G, Massa S, Musiu C, Lostia S, Demontis F, La Colla P. Artico M, et al. Among authors: sbardella g. Bioorg Med Chem Lett. 1999 Jun 21;9(12):1651-6. doi: 10.1016/s0960-894x(99)00251-6. Bioorg Med Chem Lett. 1999. PMID: 10397494
Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5-methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class.
Quaglia M, Mai A, Sbardella G, Artico M, Ragno R, Massa S, del Piano D, Setzu G, Doratiotto S, Cotichini V. Quaglia M, et al. Among authors: sbardella g. Chirality. 2001 Feb;13(2):75-80. doi: 10.1002/1520-636X(2001)13:2<75::AID-CHIR1001>3.0.CO;2-W. Chirality. 2001. PMID: 11170249
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