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134 results

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Page 1
Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist.
El-Kouhen O, Lehto SG, Pan JB, Chang R, Baker SJ, Zhong C, Hollingsworth PR, Mikusa JP, Cronin EA, Chu KL, McGaraughty SP, Uchic ME, Miller LN, Rodell NM, Patel M, Bhatia P, Mezler M, Kolasa T, Zheng GZ, Fox GB, Stewart AO, Decker MW, Moreland RB, Brioni JD, Honore P. El-Kouhen O, et al. Among authors: brioni jd. Br J Pharmacol. 2006 Nov;149(6):761-74. doi: 10.1038/sj.bjp.0706877. Epub 2006 Oct 3. Br J Pharmacol. 2006. PMID: 17016515 Free PMC article.
A-350619: a novel activator of soluble guanylyl cyclase.
Miller LN, Nakane M, Hsieh GC, Chang R, Kolasa T, Moreland RB, Brioni JD. Miller LN, et al. Life Sci. 2003 Jan 17;72(9):1015-25. doi: 10.1016/s0024-3205(02)02361-5. Life Sci. 2003. PMID: 12495780
Central mechanisms regulating penile erection in conscious rats: the dopaminergic systems related to the proerectile effect of apomorphine.
Hsieh GC, Hollingsworth PR, Martino B, Chang R, Terranova MA, O'Neill AB, Lynch JJ, Moreland RB, Donnelly-Roberts DL, Kolasa T, Mikusa JP, McVey JM, Marsh KC, Sullivan JP, Brioni JD. Hsieh GC, et al. Among authors: brioni jd. J Pharmacol Exp Ther. 2004 Jan;308(1):330-8. doi: 10.1124/jpet.103.057455. Epub 2003 Oct 20. J Pharmacol Exp Ther. 2004. PMID: 14569075
Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats.
Brioni JD, Moreland RB, Cowart M, Hsieh GC, Stewart AO, Hedlund P, Donnelly-Roberts DL, Nakane M, Lynch JJ 3rd, Kolasa T, Polakowski JS, Osinski MA, Marsh K, Andersson KE, Sullivan JP. Brioni JD, et al. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6758-63. doi: 10.1073/pnas.0308292101. Epub 2004 Apr 15. Proc Natl Acad Sci U S A. 2004. PMID: 15087502 Free PMC article.
Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.
Cowart M, Latshaw SP, Bhatia P, Daanen JF, Rohde J, Nelson SL, Patel M, Kolasa T, Nakane M, Uchic ME, Miller LN, Terranova MA, Chang R, Donnelly-Roberts DL, Namovic MT, Hollingsworth PR, Martino BR, Lynch JJ 3rd, Sullivan JP, Hsieh GC, Moreland RB, Brioni JD, Stewart AO. Cowart M, et al. Among authors: brioni jd. J Med Chem. 2004 Jul 15;47(15):3853-64. doi: 10.1021/jm030505a. J Med Chem. 2004. PMID: 15239663
134 results