Le Grice SF - Search Results

1

Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones.

Budihas SR, Gorshkova I, Gaidamakov S, Wamiru A, Bona MK, Parniak MA, Crouch RJ, McMahon JB, Beutler JA, Le Grice SF. Budihas SR, et al. Among authors: le grice sf. Nucleic Acids Res. 2005 Mar 1;33(4):1249-56. doi: 10.1093/nar/gki268. Print 2005. Nucleic Acids Res. 2005. PMID: 15741178 Free PMC article.

2

A capillary electrophoretic assay for ribonuclease H activity.

Chan KC, Budihas SR, Le Grice SF, Parniak MA, Crouch RJ, Gaidamakov SA, Isaaq HJ, Wamiru A, McMahon JB, Beutler JA. Chan KC, et al. Among authors: le grice sf. Anal Biochem. 2004 Aug 15;331(2):296-302. doi: 10.1016/j.ab.2004.05.017. Anal Biochem. 2004. PMID: 15265735

3

HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.

Bokesch HR, Wamiru A, Le Grice SF, Beutler JA, McKee TC, McMahon JB. Bokesch HR, et al. Among authors: le grice sf. J Nat Prod. 2008 Sep;71(9):1634-6. doi: 10.1021/np8002518. Epub 2008 Sep 3. J Nat Prod. 2008. PMID: 18763827 Free PMC article.

4

Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.

Chung S, Himmel DM, Jiang JK, Wojtak K, Bauman JD, Rausch JW, Wilson JA, Beutler JA, Thomas CJ, Arnold E, Le Grice SF. Chung S, et al. Among authors: le grice sf. J Med Chem. 2011 Jul 14;54(13):4462-73. doi: 10.1021/jm2000757. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21568335 Free PMC article.

5

Pre-existing distortions in nucleic acid structure aid polypurine tract selection by HIV-1 reverse transcriptase.

Kvaratskhelia M, Budihas SR, Le Grice SF. Kvaratskhelia M, et al. Among authors: le grice sf. J Biol Chem. 2002 May 10;277(19):16689-96. doi: 10.1074/jbc.M109914200. Epub 2002 Mar 1. J Biol Chem. 2002. PMID: 11875059 Free article.

6

Mutating conserved residues in the ribonuclease H domain of Ty3 reverse transcriptase affects specialized cleavage events.

Lener D, Budihas SR, Le Grice SF. Lener D, et al. Among authors: le grice sf. J Biol Chem. 2002 Jul 19;277(29):26486-95. doi: 10.1074/jbc.M200496200. Epub 2002 May 6. J Biol Chem. 2002. PMID: 11994277 Free article.

7

Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity.

Wendeler M, Lee HF, Bermingham A, Miller JT, Chertov O, Bona MK, Baichoo NS, Ehteshami M, Beutler J, O'Keefe BR, Götte M, Kvaratskhelia M, Le Grice S. Wendeler M, et al. ACS Chem Biol. 2008 Oct 17;3(10):635-44. doi: 10.1021/cb8001039. Epub 2008 Oct 3. ACS Chem Biol. 2008. PMID: 18831589 Free PMC article.

8

Identification of specific HIV-1 reverse transcriptase contacts to the viral RNA:tRNA complex by mass spectrometry and a primary amine selective reagent.

Kvaratskhelia M, Miller JT, Budihas SR, Pannell LK, Le Grice SF. Kvaratskhelia M, et al. Among authors: le grice sf. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15988-93. doi: 10.1073/pnas.252550199. Epub 2002 Dec 2. Proc Natl Acad Sci U S A. 2002. PMID: 12461175 Free PMC article.

9

A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity.

Parniak MA, Min KL, Budihas SR, Le Grice SF, Beutler JA. Parniak MA, et al. Among authors: le grice sf. Anal Biochem. 2003 Nov 1;322(1):33-9. doi: 10.1016/j.ab.2003.06.001. Anal Biochem. 2003. PMID: 14705777

10

A dimeric lactone from Ardisia japonica with inhibitory activity for HIV-1 and HIV-2 ribonuclease H.

Dat NT, Bae K, Wamiru A, McMahon JB, Le Grice SF, Bona M, Beutler JA, Kim YH. Dat NT, et al. Among authors: le grice sf. J Nat Prod. 2007 May;70(5):839-41. doi: 10.1021/np060359m. Epub 2007 Mar 31. J Nat Prod. 2007. PMID: 17397219

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