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Page 1
Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes.
Decochez K, Truyen I, van der Auwera B, Weets I, Vandemeulebroucke E, de Leeuw IH, Keymeulen B, Mathieu C, Rottiers R, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Decochez K, et al. Among authors: vandemeulebroucke e. Diabetologia. 2005 Apr;48(4):687-94. doi: 10.1007/s00125-005-1702-x. Epub 2005 Mar 9. Diabetologia. 2005. PMID: 15756536 Free article.
IA-2 autoantibodies predict impending type I diabetes in siblings of patients.
Decochez K, De Leeuw IH, Keymeulen B, Mathieu C, Rottiers R, Weets I, Vandemeulebroucke E, Truyen I, Kaufman L, Schuit FC, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Decochez K, et al. Among authors: vandemeulebroucke e. Diabetologia. 2002 Dec;45(12):1658-66. doi: 10.1007/s00125-002-0949-8. Epub 2002 Nov 12. Diabetologia. 2002. PMID: 12488955
Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes.
Truyen I, De Pauw P, Jørgensen PN, Van Schravendijk C, Ubani O, Decochez K, Vandemeulebroucke E, Weets I, Mao R, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Truyen I, et al. Among authors: vandemeulebroucke e. Diabetologia. 2005 Nov;48(11):2322-9. doi: 10.1007/s00125-005-1959-0. Epub 2005 Oct 7. Diabetologia. 2005. PMID: 16211374
Adiponectin levels do not predict clinical onset of type 1 diabetes in antibody-positive relatives.
Truyen I, De Grijse J, Van Schravendijk C, De Smet D, Decochez K, Vandemeulebroucke E, Giri M, Keymeulen B, Mathieu C, Van Gaal L, De Pauw P, Weets I, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Truyen I, et al. Among authors: vandemeulebroucke e. Diabetologia. 2007 Oct;50(10):2143-6. doi: 10.1007/s00125-007-0774-1. Epub 2007 Aug 9. Diabetologia. 2007. PMID: 17687539
Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients.
Vandemeulebroucke E, Gorus FK, Decochez K, Weets I, Keymeulen B, De Block C, Tits J, Pipeleers DG, Mathieu C; Belgian Diabetes Registry. Vandemeulebroucke E, et al. Diabetes Metab. 2009 Sep;35(4):319-27. doi: 10.1016/j.diabet.2009.02.005. Epub 2009 Jul 31. Diabetes Metab. 2009. PMID: 19647467 Clinical Trial.
Hyperglycaemic clamp test for diabetes risk assessment in IA-2-antibody-positive relatives of type 1 diabetic patients.
Vandemeulebroucke E, Keymeulen B, Decochez K, Weets I, De Block C, Féry F, Van de Velde U, Vermeulen I, De Pauw P, Mathieu C, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Vandemeulebroucke E, et al. Diabetologia. 2010 Jan;53(1):36-44. doi: 10.1007/s00125-009-1569-3. Epub 2009 Nov 7. Diabetologia. 2010. PMID: 19898832 Free article.
Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.
Keymeulen B, Walter M, Mathieu C, Kaufman L, Gorus F, Hilbrands R, Vandemeulebroucke E, Van de Velde U, Crenier L, De Block C, Candon S, Waldmann H, Ziegler AG, Chatenoud L, Pipeleers D. Keymeulen B, et al. Among authors: vandemeulebroucke e. Diabetologia. 2010 Apr;53(4):614-23. doi: 10.1007/s00125-009-1644-9. Epub 2010 Jan 14. Diabetologia. 2010. PMID: 20225393 Clinical Trial.
HLA-A*24 is an independent predictor of 5-year progression to diabetes in autoantibody-positive first-degree relatives of type 1 diabetic patients.
Mbunwe E, Van der Auwera BJ, Vermeulen I, Demeester S, Van Dalem A, Balti EV, Van Aken S, Derdelinckx L, Dorchy H, De Schepper J, van Schravendijk C, Wenzlau JM, Hutton JC, Pipeleers D, Weets I, Gorus FK; Belgian Diabetes Registry. Mbunwe E, et al. Diabetes. 2013 Apr;62(4):1345-50. doi: 10.2337/db12-0747. Epub 2012 Nov 16. Diabetes. 2013. PMID: 23160529 Free PMC article.
In antibody-positive first-degree relatives of patients with type 1 diabetes, HLA-A*24 and HLA-B*18, but not HLA-B*39, are predictors of impending diabetes with distinct HLA-DQ interactions.
Mbunwe E, Van der Auwera BJ, Weets I, Van Crombrugge P, Crenier L, Coeckelberghs M, Seret N, Decochez K, Vandemeulebroucke E, Gillard P, Keymeulen B, van Schravendijk C, Wenzlau JM, Hutton JC, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Mbunwe E, et al. Among authors: vandemeulebroucke e. Diabetologia. 2013 Sep;56(9):1964-70. doi: 10.1007/s00125-013-2951-8. Epub 2013 May 28. Diabetologia. 2013. PMID: 23712485 Free PMC article.
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