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Generation of amyloid beta protein from a presenilin-1 and betaAPP complex.
Shizuka-Ikeda M, Matsubara E, Ikeda M, Kanai M, Tomidokoro Y, Ikeda Y, Watanabe M, Kawarabayashi T, Harigaya Y, Okamoto K, Maruyama K, Castaño EM, St George-Hyslop P, Shoji M. Shizuka-Ikeda M, et al. Biochem Biophys Res Commun. 2002 Mar 29;292(2):571-8. doi: 10.1006/bbrc.2002.6681. Biochem Biophys Res Commun. 2002. PMID: 11906199
Increased production of beta-amyloid and vulnerability to endoplasmic reticulum stress by an aberrant spliced form of presenilin 2.
Sato N, Imaizumi K, Manabe T, Taniguchi M, Hitomi J, Katayama T, Yoneda T, Morihara T, Yasuda Y, Takagi T, Kudo T, Tsuda T, Itoyama Y, Makifuchi T, Fraser PE, St George-Hyslop P, Tohyama M. Sato N, et al. J Biol Chem. 2001 Jan 19;276(3):2108-14. doi: 10.1074/jbc.M006886200. Epub 2000 Oct 12. J Biol Chem. 2001. PMID: 11031265 Free article.
Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins.
Yang DS, Tandon A, Chen F, Yu G, Yu H, Arawaka S, Hasegawa H, Duthie M, Schmidt SD, Ramabhadran TV, Nixon RA, Mathews PM, Gandy SE, Mount HT, St George-Hyslop P, Fraser PE. Yang DS, et al. J Biol Chem. 2002 Aug 2;277(31):28135-42. doi: 10.1074/jbc.M110871200. Epub 2002 May 24. J Biol Chem. 2002. PMID: 12032140 Free article.
411 results