AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.
Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsuk M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, Nussenzweig A.
Petersen S, et al. Among authors: difilippantonio mj.
Nature. 2001 Dec 6;414(6864):660-665. doi: 10.1038/414660a.
Nature. 2001.
PMID: 11740565
Free PMC article.