Young KW - Search Results

1

Single cell analysis and temporal profiling of agonist-mediated inositol 1,4,5-trisphosphate, Ca2+, diacylglycerol, and protein kinase C signaling using fluorescent biosensors.

Bartlett PJ, Young KW, Nahorski SR, Challiss RA. Bartlett PJ, et al. Among authors: young kw. J Biol Chem. 2005 Jun 10;280(23):21837-46. doi: 10.1074/jbc.M411843200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15788407 Free article.

2

Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation.

Young KW, Willets JM, Parkinson MJ, Bartlett P, Spiegel S, Nahorski SR, Challiss RA. Young KW, et al. Cell Calcium. 2003 Feb;33(2):119-28. doi: 10.1016/s0143-4160(02)00205-1. Cell Calcium. 2003. PMID: 12531188

3

Role of Ca2+ feedback on single cell inositol 1,4,5-trisphosphate oscillations mediated by G-protein-coupled receptors.

Young KW, Nash MS, Challiss RA, Nahorski SR. Young KW, et al. J Biol Chem. 2003 Jun 6;278(23):20753-60. doi: 10.1074/jbc.M211555200. Epub 2003 Apr 1. J Biol Chem. 2003. PMID: 12670945 Free article.

4

Visualizing phosphoinositide signalling in single neurons gets a green light.

Nahorski SR, Young KW, John Challiss RA, Nash MS. Nahorski SR, et al. Among authors: young kw. Trends Neurosci. 2003 Aug;26(8):444-52. doi: 10.1016/S0166-2236(03)00178-4. Trends Neurosci. 2003. PMID: 12900176 Review.

5

NMDA-receptor regulation of muscarinic-receptor stimulated inositol 1,4,5-trisphosphate production and protein kinase C activation in single cerebellar granule neurons.

Young KW, Garro MA, Challiss RA, Nahorski SR. Young KW, et al. J Neurochem. 2004 Jun;89(6):1537-46. doi: 10.1111/j.1471-4159.2004.02458.x. J Neurochem. 2004. PMID: 15189357 Free article.

6

Altered expression of G(q/11alpha) protein shapes mGlu1 and mGlu5 receptor-mediated single cell inositol 1,4,5-trisphosphate and Ca(2+) signaling.

Atkinson PJ, Young KW, Ennion SJ, Kew JN, Nahorski SR, Challiss RA. Atkinson PJ, et al. Among authors: young kw. Mol Pharmacol. 2006 Jan;69(1):174-84. doi: 10.1124/mol.105.014258. Epub 2005 Oct 18. Mol Pharmacol. 2006. PMID: 16234485

7

Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent on sphingosine kinase activation.

Young KW, Challiss RA, Nahorski SR, MacKrill JJ. Young KW, et al. Biochem J. 1999 Oct 1;343 Pt 1(Pt 1):45-52. Biochem J. 1999. PMID: 10493910 Free PMC article.

8

Lysophosphatidic acid-induced Ca2+ mobilization requires intracellular sphingosine 1-phosphate production. Potential involvement of endogenous EDG-4 receptors.

Young KW, Bootman MD, Channing DR, Lipp P, Maycox PR, Meakin J, Challiss RA, Nahorski SR. Young KW, et al. J Biol Chem. 2000 Dec 8;275(49):38532-9. doi: 10.1074/jbc.M006631200. J Biol Chem. 2000. PMID: 10954727 Free article.

9

Reassessment of the Ca2+ sensing property of a type I metabotropic glutamate receptor by simultaneous measurement of inositol 1,4,5-trisphosphate and Ca2+ in single cells.

Nash MS, Saunders R, Young KW, Challiss RA, Nahorski SR. Nash MS, et al. Among authors: young kw. J Biol Chem. 2001 Jun 1;276(22):19286-93. doi: 10.1074/jbc.M007600200. Epub 2001 Feb 20. J Biol Chem. 2001. PMID: 11278354 Free article.

10

Single-cell imaging of graded Ins(1,4,5)P3 production following G-protein-coupled-receptor activation.

Nash MS, Young KW, Willars GB, Challiss RA, Nahorski SR. Nash MS, et al. Among authors: young kw. Biochem J. 2001 May 15;356(Pt 1):137-42. doi: 10.1042/0264-6021:3560137. Biochem J. 2001. PMID: 11336645 Free PMC article.

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