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Direct intramyocardial plasmid vascular endothelial growth factor-A165 gene therapy in patients with stable severe angina pectoris A randomized double-blind placebo-controlled study: the Euroinject One trial.
Kastrup J, Jørgensen E, Rück A, Tägil K, Glogar D, Ruzyllo W, Bøtker HE, Dudek D, Drvota V, Hesse B, Thuesen L, Blomberg P, Gyöngyösi M, Sylvén C; Euroinject One Group. Kastrup J, et al. Among authors: ruck a. J Am Coll Cardiol. 2005 Apr 5;45(7):982-8. doi: 10.1016/j.jacc.2004.12.068. J Am Coll Cardiol. 2005. PMID: 15808751 Free article. Clinical Trial.
Effects of intramyocardial injection of phVEGF-A165 as sole therapy in patients with refractory coronary artery disease--12-month follow-up: angiogenic gene therapy.
Sarkar N, Rück A, Källner G, Y-Hassan S, Blomberg P, Islam KB, van der Linden J, Lindblom D, Nygren AT, Lind B, Brodin LA, Drvota V, Sylvén C. Sarkar N, et al. Among authors: ruck a. J Intern Med. 2001 Nov;250(5):373-81. doi: 10.1046/j.1365-2796.2001.00905.x. J Intern Med. 2001. PMID: 11887971 Free article. Clinical Trial.
NOGA-guided analysis of regional myocardial perfusion abnormalities treated with intramyocardial injections of plasmid encoding vascular endothelial growth factor A-165 in patients with chronic myocardial ischemia: subanalysis of the EUROINJECT-ONE multicenter double-blind randomized study.
Gyöngyösi M, Khorsand A, Zamini S, Sperker W, Strehblow C, Kastrup J, Jorgensen E, Hesse B, Tägil K, Bøtker HE, Ruzyllo W, Teresiñska A, Dudek D, Hubalewska A, Rück A, Nielsen SS, Graf S, Mundigler G, Novak J, Sochor H, Maurer G, Glogar D, Sylven C. Gyöngyösi M, et al. Among authors: ruck a. Circulation. 2005 Aug 30;112(9 Suppl):I157-65. doi: 10.1161/01.CIRCULATIONAHA.105.525782. Circulation. 2005. PMID: 16159809 Clinical Trial.
Randomized trials are also essential for device therapy.
Rück A, Sylvén C. Rück A, et al. J Intern Med. 2006 Sep;260(3):281; author reply 282-3. doi: 10.1111/j.1365-2796.2006.01681.x. J Intern Med. 2006. PMID: 16918826 Free article. No abstract available.
Therapeutic angiogenesis gains a leg to stand on.
Rück A, Sylvén C. Rück A, et al. Mol Ther. 2008 May;16(5):808-10. doi: 10.1038/mt.2008.65. Mol Ther. 2008. PMID: 18432271 Free article. No abstract available.
174 results