Spear ED - Search Results

1

Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation.

Spear ED, Ng DT. Spear ED, et al. J Cell Biol. 2005 Apr 11;169(1):73-82. doi: 10.1083/jcb.200411136. Epub 2005 Apr 4. J Cell Biol. 2005. PMID: 15809311 Free PMC article.

2

The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control.

Ng DT, Spear ED, Walter P. Ng DT, et al. Among authors: spear ed. J Cell Biol. 2000 Jul 10;150(1):77-88. doi: 10.1083/jcb.150.1.77. J Cell Biol. 2000. PMID: 10893258 Free PMC article.

3

The unfolded protein response: no longer just a special teams player.

Spear E, Ng DT. Spear E, et al. Traffic. 2001 Aug;2(8):515-23. doi: 10.1034/j.1600-0854.2001.20801.x. Traffic. 2001. PMID: 11489209 Free article. Review.

4

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding.

Vashist S, Kim W, Belden WJ, Spear ED, Barlowe C, Ng DT. Vashist S, et al. Among authors: spear ed. J Cell Biol. 2001 Oct 29;155(3):355-68. doi: 10.1083/jcb.200106123. Epub 2001 Oct 22. J Cell Biol. 2001. PMID: 11673477 Free PMC article.

5

Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways.

Spear ED, Ng DT. Spear ED, et al. Mol Biol Cell. 2003 Jul;14(7):2756-67. doi: 10.1091/mbc.e02-11-0717. Epub 2003 Mar 20. Mol Biol Cell. 2003. PMID: 12857862 Free PMC article.

6

Yos9p detects and targets misfolded glycoproteins for ER-associated degradation.

Kim W, Spear ED, Ng DT. Kim W, et al. Among authors: spear ed. Mol Cell. 2005 Sep 16;19(6):753-64. doi: 10.1016/j.molcel.2005.08.010. Mol Cell. 2005. PMID: 16168371 Free article.

7

Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.

Maurer MJ, Spear ED, Yu AT, Lee EJ, Shahzad S, Michaelis S. Maurer MJ, et al. Among authors: spear ed. G3 (Bethesda). 2016 Jul 7;6(7):1853-66. doi: 10.1534/g3.116.027953. G3 (Bethesda). 2016. PMID: 27172186 Free PMC article.

8

Structural conservation of components in the amino acid sensing branch of the TOR pathway in yeast and mammals.

Kogan K, Spear ED, Kaiser CA, Fass D. Kogan K, et al. Among authors: spear ed. J Mol Biol. 2010 Sep 17;402(2):388-98. doi: 10.1016/j.jmb.2010.07.034. Epub 2010 Jul 23. J Mol Biol. 2010. PMID: 20655927

9

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability.

Spear ED, Hsu ET, Nie L, Carpenter EP, Hrycyna CA, Michaelis S. Spear ED, et al. Dis Model Mech. 2018 Jul 13;11(7):dmm033670. doi: 10.1242/dmm.033670. Dis Model Mech. 2018. PMID: 29794150 Free PMC article.

10

A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24.

Spear ED, Alford RF, Babatz TD, Wood KM, Mossberg OW, Odinammadu K, Shilagardi K, Gray JJ, Michaelis S. Spear ED, et al. Methods. 2019 Mar 15;157:47-55. doi: 10.1016/j.ymeth.2019.01.001. Epub 2019 Jan 6. Methods. 2019. PMID: 30625386 Free PMC article. Review.

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