Sexton PM - Search Results

1

G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor.

Kostenis E, Milligan G, Christopoulos A, Sanchez-Ferrer CF, Heringer-Walther S, Sexton PM, Gembardt F, Kellett E, Martini L, Vanderheyden P, Schultheiss HP, Walther T. Kostenis E, et al. Among authors: sexton pm. Circulation. 2005 Apr 12;111(14):1806-13. doi: 10.1161/01.CIR.0000160867.23556.7D. Epub 2005 Apr 4. Circulation. 2005. PMID: 15809376

2

RAMPs: 5 years on, where to now?

Morfis M, Christopoulos A, Sexton PM. Morfis M, et al. Among authors: sexton pm. Trends Pharmacol Sci. 2003 Nov;24(11):596-601. doi: 10.1016/j.tips.2003.09.001. Trends Pharmacol Sci. 2003. PMID: 14607083 Review.

3

Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptors.

Avlani V, May LT, Sexton PM, Christopoulos A. Avlani V, et al. Among authors: sexton pm. J Pharmacol Exp Ther. 2004 Mar;308(3):1062-72. doi: 10.1124/jpet.103.059840. Epub 2004 Jan 7. J Pharmacol Exp Ther. 2004. PMID: 14711931

4

Allosteric modulation of G protein-coupled receptors.

May LT, Avlani VA, Sexton PM, Christopoulos A. May LT, et al. Among authors: sexton pm. Curr Pharm Des. 2004;10(17):2003-13. doi: 10.2174/1381612043384303. Curr Pharm Des. 2004. PMID: 15279541 Review.

5

Regulation of M2 muscarinic acetylcholine receptor expression and signaling by prolonged exposure to allosteric modulators.

May LT, Lin Y, Sexton PM, Christopoulos A. May LT, et al. Among authors: sexton pm. J Pharmacol Exp Ther. 2005 Jan;312(1):382-90. doi: 10.1124/jpet.104.073767. Epub 2004 Aug 27. J Pharmacol Exp Ther. 2005. PMID: 15333678

6

Regulation of serotonin 5-HT2C receptors by chronic ligand exposure.

Devlin MG, Smith NJ, Ryan OM, Guida E, Sexton PM, Christopoulos A. Devlin MG, et al. Among authors: sexton pm. Eur J Pharmacol. 2004 Sep 13;498(1-3):59-69. doi: 10.1016/j.ejphar.2004.07.102. Eur J Pharmacol. 2004. PMID: 15363976

7

Amylin receptors: molecular composition and pharmacology.

Hay DL, Christopoulos G, Christopoulos A, Sexton PM. Hay DL, et al. Among authors: sexton pm. Biochem Soc Trans. 2004 Nov;32(Pt 5):865-7. doi: 10.1042/BST0320865. Biochem Soc Trans. 2004. PMID: 15494035 Review.

8

G-protein-coupled receptor allosterism: the promise and the problem(s).

Christopoulos A, May LT, Avlani VA, Sexton PM. Christopoulos A, et al. Among authors: sexton pm. Biochem Soc Trans. 2004 Nov;32(Pt 5):873-7. doi: 10.1042/BST0320873. Biochem Soc Trans. 2004. PMID: 15494038 Review.

9

"Ins and outs" of seven-transmembrane receptor signalling to ERK.

Werry TD, Sexton PM, Christopoulos A. Werry TD, et al. Among authors: sexton pm. Trends Endocrinol Metab. 2005 Jan-Feb;16(1):26-33. doi: 10.1016/j.tem.2004.11.008. Trends Endocrinol Metab. 2005. PMID: 15620546 Review.

10

Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes.

Hay DL, Christopoulos G, Christopoulos A, Poyner DR, Sexton PM. Hay DL, et al. Among authors: sexton pm. Mol Pharmacol. 2005 May;67(5):1655-65. doi: 10.1124/mol.104.008615. Epub 2005 Feb 3. Mol Pharmacol. 2005. PMID: 15692146

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