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9,683 results

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Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin.
Yonemori K, Ueno H, Okusaka T, Yamamoto N, Ikeda M, Saijo N, Yoshida T, Ishii H, Furuse J, Sugiyama E, Kim SR, Kikura-Hanajiri R, Hasegawa R, Saito Y, Ozawa S, Kaniwa N, Sawada J. Yonemori K, et al. Among authors: saito y. Clin Cancer Res. 2005 Apr 1;11(7):2620-4. doi: 10.1158/1078-0432.CCR-04-1497. Clin Cancer Res. 2005. PMID: 15814642 Clinical Trial.
Identification of a predictive biomarker for hematologic toxicities of gemcitabine.
Matsubara J, Ono M, Negishi A, Ueno H, Okusaka T, Furuse J, Furuta K, Sugiyama E, Saito Y, Kaniwa N, Sawada J, Honda K, Sakuma T, Chiba T, Saijo N, Hirohashi S, Yamada T. Matsubara J, et al. Among authors: saito y. J Clin Oncol. 2009 May 1;27(13):2261-8. doi: 10.1200/JCO.2008.19.9745. Epub 2009 Mar 16. J Clin Oncol. 2009. PMID: 19289617
Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms.
Sugiyama E, Kaniwa N, Kim SR, Hasegawa R, Saito Y, Ueno H, Okusaka T, Ikeda M, Morizane C, Kondo S, Yamamoto N, Tamura T, Furuse J, Ishii H, Yoshida T, Saijo N, Sawada J. Sugiyama E, et al. Among authors: saito y. Clin Pharmacokinet. 2010 Aug;49(8):549-58. doi: 10.2165/11532970-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20608756
UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer.
Sai K, Saeki M, Saito Y, Ozawa S, Katori N, Jinno H, Hasegawa R, Kaniwa N, Sawada J, Komamura K, Ueno K, Kamakura S, Kitakaze M, Kitamura Y, Kamatani N, Minami H, Ohtsu A, Shirao K, Yoshida T, Saijo N. Sai K, et al. Among authors: saito y. Clin Pharmacol Ther. 2004 Jun;75(6):501-15. doi: 10.1016/j.clpt.2004.01.010. Clin Pharmacol Ther. 2004. PMID: 15179405
Novel nonsynonymous single nucleotide polymorphisms in the CYP2D6 gene.
Soyama A, Kubo T, Miyajima A, Saito Y, Shiseki K, Komamura K, Ueno K, Kamakura S, Kitakaze M, Tomoike H, Ozawa S, Sawada J. Soyama A, et al. Among authors: saito y. Drug Metab Pharmacokinet. 2004 Aug;19(4):313-9. doi: 10.2133/dmpk.19.313. Drug Metab Pharmacokinet. 2004. PMID: 15499201 Free article.
Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.
Nakajima Y, Saito Y, Shiseki K, Fukushima-Uesaka H, Hasegawa R, Ozawa S, Sugai K, Katoh M, Saitoh O, Ohnuma T, Kawai M, Ohtsuki T, Suzuki C, Minami N, Kimura H, Goto Y, Kamatani N, Kaniwa N, Sawada J. Nakajima Y, et al. Among authors: saito y. Eur J Clin Pharmacol. 2005 Mar;61(1):25-34. doi: 10.1007/s00228-004-0878-1. Epub 2005 Feb 4. Eur J Clin Pharmacol. 2005. PMID: 15692831 Clinical Trial.
9,683 results