Constantinou-Kokotou V - Search Results

1

Enzymatic removal of carboxyl protecting groups. 1. Cleavage of the tert-butyl moiety.

Schmidt M, Barbayianni E, Fotakopoulou I, Höhne M, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G. Schmidt M, et al. J Org Chem. 2005 Apr 29;70(9):3737-40. doi: 10.1021/jo050114z. J Org Chem. 2005. PMID: 15845019

2

Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties.

Barbayianni E, Fotakopoulou I, Schmidt M, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G. Barbayianni E, et al. J Org Chem. 2005 Oct 28;70(22):8730-3. doi: 10.1021/jo051004v. J Org Chem. 2005. PMID: 16238302

3

Enzymatic removal of carboxyl protecting groups. III. Fast removal of allyl and chloroethyl esters by Bacillus subtilis esterase (BS2).

Fotakopoulou I, Barbayianni E, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G. Fotakopoulou I, et al. J Org Chem. 2007 Feb 2;72(3):782-6. doi: 10.1021/jo061871f. J Org Chem. 2007. PMID: 17253795

4

Synthesis of optically active lipidic alpha-amino acids and lipidic 2-amino alcohols.

Constantinou-Kokotou V, Kokotos G. Constantinou-Kokotou V, et al. Amino Acids. 1999;16(3-4):273-85. doi: 10.1007/BF01388172. Amino Acids. 1999. PMID: 10399016 Review.

5

Differential inhibition of group IVA and group VIA phospholipases A2 by 2-oxoamides.

Stephens D, Barbayianni E, Constantinou-Kokotou V, Peristeraki A, Six DA, Cooper J, Harkewicz R, Deems RA, Dennis EA, Kokotos G. Stephens D, et al. J Med Chem. 2006 May 4;49(9):2821-8. doi: 10.1021/jm050993h. J Med Chem. 2006. PMID: 16640343 Free PMC article.

6

Synthesis and study of a lipophilic alpha-keto amide inhibitor of pancreatic lipase.

Chiou A, Markidis T, Constantinou-Kokotou V, Verger R, Kokotos G. Chiou A, et al. Org Lett. 2000 Feb 10;2(3):347-50. doi: 10.1021/ol991295s. Org Lett. 2000. PMID: 10814319

7

Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2.

Six DA, Barbayianni E, Loukas V, Constantinou-Kokotou V, Hadjipavlou-Litina D, Stephens D, Wong AC, Magrioti V, Moutevelis-Minakakis P, Baker SF, Dennis EA, Kokotos G. Six DA, et al. J Med Chem. 2007 Aug 23;50(17):4222-35. doi: 10.1021/jm0613673. Epub 2007 Aug 2. J Med Chem. 2007. PMID: 17672443

8

Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A(2) enzymes.

Antonopoulou G, Barbayianni E, Magrioti V, Cotton N, Stephens D, Constantinou-Kokotou V, Dennis EA, Kokotos G. Antonopoulou G, et al. Bioorg Med Chem. 2008 Dec 15;16(24):10257-69. doi: 10.1016/j.bmc.2008.10.046. Epub 2008 Nov 1. Bioorg Med Chem. 2008. PMID: 18993078 Free PMC article.

9

Inhibition of group IVA cytosolic phospholipase A2 by thiazolyl ketones in vitro, ex vivo, and in vivo.

Kokotos G, Feuerherm AJ, Barbayianni E, Shah I, Sæther M, Magrioti V, Nguyen T, Constantinou-Kokotou V, Dennis EA, Johansen B. Kokotos G, et al. Among authors: constantinou kokotou v. J Med Chem. 2014 Sep 25;57(18):7523-35. doi: 10.1021/jm500192s. Epub 2014 Sep 3. J Med Chem. 2014. PMID: 25152071 Free article.

10

2-Oxoamides based on dipeptides as selective calcium-independent phospholipase A₂ inhibitors.

Smyrniotou A, Kokotou MG, Mouchlis VD, Barbayianni E, Kokotos G, Dennis EA, Constantinou-Kokotou V. Smyrniotou A, et al. Among authors: constantinou kokotou v. Bioorg Med Chem. 2017 Feb 1;25(3):926-940. doi: 10.1016/j.bmc.2016.12.007. Epub 2016 Dec 8. Bioorg Med Chem. 2017. PMID: 28034646 Free PMC article.

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