Bernardi P - Search Results

1

Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.

Cusan C, Spalluto G, Prato M, Adams M, Bodensieck A, Bauer R, Tubaro A, Bernardi P, Da Ros T. Cusan C, et al. Among authors: bernardi p. Farmaco. 2005 Apr;60(4):327-32. doi: 10.1016/j.farmac.2004.12.009. Farmaco. 2005. PMID: 15848208

2

Synthesis and biological evaluation of new phenidone analogues as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.

Cusan C, Spalluto G, Prato M, Adams M, Bodensieck A, Bauer R, Tubaro A, Bernardi P, Da Ros T. Cusan C, et al. Among authors: bernardi p. Farmaco. 2005 Jan;60(1):7-13. doi: 10.1016/j.farmac.2004.09.002. Epub 2004 Dec 24. Farmaco. 2005. PMID: 15652362

3

Peptide-based carbon nanotubes for mitochondrial targeting.

Battigelli A, Russier J, Venturelli E, Fabbro C, Petronilli V, Bernardi P, Da Ros T, Prato M, Bianco A. Battigelli A, et al. Among authors: bernardi p. Nanoscale. 2013 Oct 7;5(19):9110-7. doi: 10.1039/c3nr02694a. Epub 2013 Aug 1. Nanoscale. 2013. PMID: 23903095

4

Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors.

Gugliucci A, Ranzato L, Scorrano L, Colonna R, Petronilli V, Cusan C, Prato M, Mancini M, Pagano F, Bernardi P. Gugliucci A, et al. Among authors: bernardi p. J Biol Chem. 2002 Aug 30;277(35):31789-95. doi: 10.1074/jbc.M204450200. Epub 2002 Jun 21. J Biol Chem. 2002. PMID: 12080072 Free article.

Treatment with 1 microM MK886 plus indomethacin sensitized cells to killing by exogenous arachidonic acid, which induces PTP opening and cytochrome c release (Scorrano, L., Penzo, D., Petronilli, V., Pagano, F., and Bernardi, P. (2001) J. Biol. Chem. 276, 12035-1204 …

Treatment with 1 microM MK886 plus indomethacin sensitized cells to killing by exogenous arachidonic acid, which induces PTP opening and cyt …

5

Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway.

Penzo D, Petronilli V, Angelin A, Cusan C, Colonna R, Scorrano L, Pagano F, Prato M, Di Lisa F, Bernardi P. Penzo D, et al. Among authors: bernardi p. J Biol Chem. 2004 Jun 11;279(24):25219-25. doi: 10.1074/jbc.M310381200. Epub 2004 Apr 7. J Biol Chem. 2004. PMID: 15070903 Free article.

6

The idebenone metabolite QS10 restores electron transfer in complex I and coenzyme Q defects.

Giorgio V, Schiavone M, Galber C, Carini M, Da Ros T, Petronilli V, Argenton F, Carelli V, Acosta Lopez MJ, Salviati L, Prato M, Bernardi P. Giorgio V, et al. Among authors: bernardi p. Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):901-908. doi: 10.1016/j.bbabio.2018.04.006. Epub 2018 Apr 22. Biochim Biophys Acta Bioenerg. 2018. PMID: 29694828 Free article.

7

Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction.

Dodoni G, Canton M, Petronilli V, Bernardi P, Di Lisa F. Dodoni G, et al. Among authors: bernardi p. Biochim Biophys Acta. 2004 Jul 23;1658(1-2):58-63. doi: 10.1016/j.bbabio.2004.05.005. Biochim Biophys Acta. 2004. PMID: 15282175 Free article.

8

Serenoa repens extract targets mitochondria and activates the intrinsic apoptotic pathway in human prostate cancer cells.

Baron A, Mancini M, Caldwell E, Cabrelle A, Bernardi P, Pagano F. Baron A, et al. Among authors: bernardi p. BJU Int. 2009 May;103(9):1275-83. doi: 10.1111/j.1464-410X.2008.08266.x. Epub 2009 Jan 14. BJU Int. 2009. PMID: 19154468

9

Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations.

Bernardi P, Vassanelli S, Veronese P, Colonna R, Szabó I, Zoratti M. Bernardi P, et al. J Biol Chem. 1992 Feb 15;267(5):2934-9. J Biol Chem. 1992. PMID: 1737749 Free article.

Since PhAsO induces the PTP even in the presence of excess EGTA and in the absence of respiration (Lenartowicz, E., Bernardi, P., and Azzone, G.F. (1991) J. Bioenerg. Biomembr. 23, 679-688), we have been able to study the Ca2+ dependence of the induction process. .. …

Since PhAsO induces the PTP even in the presence of excess EGTA and in the absence of respiration (Lenartowicz, E., Bernardi, P …

10

Bupivacaine myotoxicity is mediated by mitochondria.

Irwin W, Fontaine E, Agnolucci L, Penzo D, Betto R, Bortolotto S, Reggiani C, Salviati G, Bernardi P. Irwin W, et al. Among authors: bernardi p. J Biol Chem. 2002 Apr 5;277(14):12221-7. doi: 10.1074/jbc.M108938200. Epub 2002 Jan 14. J Biol Chem. 2002. PMID: 11790774 Free article.

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