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Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication.
Emiliani S, Mousnier A, Busschots K, Maroun M, Van Maele B, Tempé D, Vandekerckhove L, Moisant F, Ben-Slama L, Witvrouw M, Christ F, Rain JC, Dargemont C, Debyser Z, Benarous R. Emiliani S, et al. Among authors: busschots k. J Biol Chem. 2005 Jul 8;280(27):25517-23. doi: 10.1074/jbc.M501378200. Epub 2005 Apr 25. J Biol Chem. 2005. PMID: 15855167 Free article.
The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding.
Busschots K, Vercammen J, Emiliani S, Benarous R, Engelborghs Y, Christ F, Debyser Z. Busschots K, et al. J Biol Chem. 2005 May 6;280(18):17841-7. doi: 10.1074/jbc.M411681200. Epub 2005 Mar 4. J Biol Chem. 2005. PMID: 15749713 Free article.
Chem. 278, 372-381; Maertens, G., Cherepanov, P., Pluymers, W., Busschots, K., De Clercq, E., Debyser, Z., and Engelborghs, Y. (2003) J. Biol. Chem. 278, 33528-33539). ...
Chem. 278, 372-381; Maertens, G., Cherepanov, P., Pluymers, W., Busschots, K., De Clercq, E., Debyser, Z., and Engelborghs, Y. …
Cellular co-factors of HIV-1 integration.
Van Maele B, Busschots K, Vandekerckhove L, Christ F, Debyser Z. Van Maele B, et al. Among authors: busschots k. Trends Biochem Sci. 2006 Feb;31(2):98-105. doi: 10.1016/j.tibs.2005.12.002. Epub 2006 Jan 5. Trends Biochem Sci. 2006. PMID: 16403635 Review.
Identification of the LEDGF/p75 binding site in HIV-1 integrase.
Busschots K, Voet A, De Maeyer M, Rain JC, Emiliani S, Benarous R, Desender L, Debyser Z, Christ F. Busschots K, et al. J Mol Biol. 2007 Feb 2;365(5):1480-92. doi: 10.1016/j.jmb.2006.10.094. Epub 2006 Nov 3. J Mol Biol. 2007. PMID: 17137594
Y-box-binding protein 1 supports the early and late steps of HIV replication.
Weydert C, van Heertum B, Dirix L, De Houwer S, De Wit F, Mast J, Husson SJ, Busschots K, König R, Gijsbers R, De Rijck J, Debyser Z. Weydert C, et al. Among authors: busschots k. PLoS One. 2018 Jul 11;13(7):e0200080. doi: 10.1371/journal.pone.0200080. eCollection 2018. PLoS One. 2018. PMID: 29995936 Free PMC article.
15 results