Zimmerman KM - Search Results

1

3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists.

Neel DA, Brown ML, Lander PA, Grese TA, Defauw JM, Doti RA, Fields T, Kelley SA, Smith S, Zimmerman KM, Steinberg MI, Jadhav PK. Neel DA, et al. Among authors: zimmerman km. Bioorg Med Chem Lett. 2005 May 16;15(10):2553-7. doi: 10.1016/j.bmcl.2005.03.086. Bioorg Med Chem Lett. 2005. PMID: 15863315

2

(S)-N-{3-[1-cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl}-methanesulfonamide: a potent, nonsteroidal, functional antagonist of the mineralocorticoid receptor.

Bell MG, Gernert DL, Grese TA, Belvo MD, Borromeo PS, Kelley SA, Kennedy JH, Kolis SP, Lander PA, Richey R, Sharp VS, Stephenson GA, Williams JD, Yu H, Zimmerman KM, Steinberg MI, Jadhav PK. Bell MG, et al. Among authors: zimmerman km. J Med Chem. 2007 Dec 27;50(26):6443-5. doi: 10.1021/jm701186z. Epub 2007 Nov 27. J Med Chem. 2007. PMID: 18038968

3

Structural evolution and pharmacology of a novel series of triacid angiotensin II receptor antagonists.

Palkowitz AD, Steinberg MI, Thrasher KJ, Reel JK, Hauser KL, Zimmerman KM, Wiest SA, Whitesitt CA, Simon RL, Pfeifer W, et al. Palkowitz AD, et al. Among authors: zimmerman km. J Med Chem. 1994 Dec 23;37(26):4508-21. doi: 10.1021/jm00052a010. J Med Chem. 1994. PMID: 7799401

4

Nonpeptide angiotensin II receptor antagonists: synthetic and computational chemistry of N-[[4-[2-(2H-tetrazol-5-yl)-1-cycloalken-1- yl]phenyl]methyl]imidazole derivatives and their in vitro activity.

Lin HS, Rampersaud AA, Zimmerman K, Steinberg MI, Boyd DB. Lin HS, et al. J Med Chem. 1992 Jul 10;35(14):2658-67. doi: 10.1021/jm00092a017. J Med Chem. 1992. PMID: 1635064

5

Characterization of distinct angiotensin II binding sites in rat adrenal gland and bovine cerebellum using selective nonpeptide antagonists.

Wiest SA, Rampersaud A, Zimmerman K, Steinberg MI. Wiest SA, et al. J Cardiovasc Pharmacol. 1991 Feb;17(2):177-84. doi: 10.1097/00005344-199102000-00001. J Cardiovasc Pharmacol. 1991. PMID: 1709220

6

Identification, synthesis and pharmacological activity of moxonidine metabolites.

Wirth DD, He MM, Czeskis BA, Zimmerman KM, Roettig U, Stenzel W, Steinberg MI. Wirth DD, et al. Among authors: zimmerman km. Eur J Med Chem. 2002 Jan;37(1):23-34. doi: 10.1016/s0223-5234(01)01293-4. Eur J Med Chem. 2002. PMID: 11841872

7

Losartan, a nonpeptide angiotensin II (Ang II) receptor antagonist, inhibits neointima formation following balloon injury to rat carotid arteries.

Kauffman RF, Bean JS, Zimmerman KM, Brown RF, Steinberg MI. Kauffman RF, et al. Among authors: zimmerman km. Life Sci. 1991;49(25):PL223-8. doi: 10.1016/0024-3205(91)90298-p. Life Sci. 1991. PMID: 1745100

8

Binding and pharmacologic properties of peptides derived from human and rat angiotensin II (AII) mRNA.

Wiest SA, Gesellchen PD, Zimmerman K, Steinberg MI. Wiest SA, et al. Biochem Biophys Res Commun. 1990 Jul 31;170(2):462-9. doi: 10.1016/0006-291x(90)92114-f. Biochem Biophys Res Commun. 1990. PMID: 1974420

9

Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure.

Cao G, Beyer TP, Zhang Y, Schmidt RJ, Chen YQ, Cockerham SL, Zimmerman KM, Karathanasis SK, Cannady EA, Fields T, Mantlo NB. Cao G, et al. Among authors: zimmerman km. J Lipid Res. 2011 Dec;52(12):2169-2176. doi: 10.1194/jlr.M018069. Epub 2011 Sep 25. J Lipid Res. 2011. PMID: 21957197 Free PMC article.

10

Metabolic and hemodynamic effects of moxonidine in the Zucker diabetic fatty rat model of type 2 diabetes.

Yakubu-Madus FE, Johnson WT, Zimmerman KM, Dananberg J, Steinberg MI. Yakubu-Madus FE, et al. Among authors: zimmerman km. Diabetes. 1999 May;48(5):1093-100. doi: 10.2337/diabetes.48.5.1093. Diabetes. 1999. PMID: 10331415

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