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Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.
Noble W, Planel E, Zehr C, Olm V, Meyerson J, Suleman F, Gaynor K, Wang L, LaFrancois J, Feinstein B, Burns M, Krishnamurthy P, Wen Y, Bhat R, Lewis J, Dickson D, Duff K. Noble W, et al. Among authors: burns m. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6990-5. doi: 10.1073/pnas.0500466102. Epub 2005 May 2. Proc Natl Acad Sci U S A. 2005. PMID: 15867159 Free PMC article.
Cdk5 is a key factor in tau aggregation and tangle formation in vivo.
Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K, LaFrancois J, Wang L, Kondo T, Davies P, Burns M, Veeranna, Nixon R, Dickson D, Matsuoka Y, Ahlijanian M, Lau LF, Duff K. Noble W, et al. Among authors: burns m. Neuron. 2003 May 22;38(4):555-65. doi: 10.1016/s0896-6273(03)00259-9. Neuron. 2003. PMID: 12765608 Free article.
Brain on steroids resists neurodegeneration.
Burns MP, Duff K. Burns MP, et al. Nat Med. 2004 Jul;10(7):675-6. doi: 10.1038/nm0704-675. Nat Med. 2004. PMID: 15229510 No abstract available.
Challenges in neurodegeneration research.
Noble W, Burns MP. Noble W, et al. Front Psychiatry. 2010 Mar 10;1:7. doi: 10.3389/fpsyt.2010.00007. eCollection 2010. Front Psychiatry. 2010. PMID: 21423419 Free PMC article. No abstract available.
1,562 results