Krishnamurthy P - Search Results

1

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.

Noble W, Planel E, Zehr C, Olm V, Meyerson J, Suleman F, Gaynor K, Wang L, LaFrancois J, Feinstein B, Burns M, Krishnamurthy P, Wen Y, Bhat R, Lewis J, Dickson D, Duff K. Noble W, et al. Among authors: krishnamurthy p. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6990-5. doi: 10.1073/pnas.0500466102. Epub 2005 May 2. Proc Natl Acad Sci U S A. 2005. PMID: 15867159 Free PMC article.

2

Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia.

Planel E, Richter KE, Nolan CE, Finley JE, Liu L, Wen Y, Krishnamurthy P, Herman M, Wang L, Schachter JB, Nelson RB, Lau LF, Duff KE. Planel E, et al. Among authors: krishnamurthy p. J Neurosci. 2007 Mar 21;27(12):3090-7. doi: 10.1523/JNEUROSCI.4854-06.2007. J Neurosci. 2007. PMID: 17376970 Free PMC article.

3

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing.

Wen Y, Yu WH, Maloney B, Bailey J, Ma J, Marié I, Maurin T, Wang L, Figueroa H, Herman M, Krishnamurthy P, Liu L, Planel E, Lau LF, Lahiri DK, Duff K. Wen Y, et al. Among authors: krishnamurthy p. Neuron. 2008 Mar 13;57(5):680-90. doi: 10.1016/j.neuron.2008.02.024. Neuron. 2008. PMID: 18341989 Free PMC article.

4

A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment.

Liu L, Orozco IJ, Planel E, Wen Y, Bretteville A, Krishnamurthy P, Wang L, Herman M, Figueroa H, Yu WH, Arancio O, Duff K. Liu L, et al. Among authors: krishnamurthy p. Neurobiol Dis. 2008 Jul;31(1):46-57. doi: 10.1016/j.nbd.2008.03.005. Epub 2008 Apr 7. Neurobiol Dis. 2008. PMID: 18504134 Free PMC article.

5

Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo.

Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, Kumar A, Bretteville A, Figueroa HY, Yu WH, Whittington RA, Davies P, Takashima A, Nixon RA, Duff KE. Planel E, et al. Among authors: krishnamurthy p. J Neurosci. 2008 Nov 26;28(48):12798-807. doi: 10.1523/JNEUROSCI.4101-08.2008. J Neurosci. 2008. PMID: 19036972 Free PMC article.

6

Non-invasive, in vivo monitoring of neuronal transport impairment in a mouse model of tauopathy using MEMRI.

Bertrand A, Khan U, Hoang DM, Novikov DS, Krishnamurthy P, Rajamohamed Sait HB, Little BW, Sigurdsson EM, Wadghiri YZ. Bertrand A, et al. Among authors: krishnamurthy p. Neuroimage. 2013 Jan 1;64:693-702. doi: 10.1016/j.neuroimage.2012.08.065. Epub 2012 Aug 31. Neuroimage. 2013. PMID: 22960250 Free PMC article.

7

Tau as a therapeutic target for Alzheimer's disease.

Boutajangout A, Sigurdsson EM, Krishnamurthy PK. Boutajangout A, et al. Among authors: krishnamurthy pk. Curr Alzheimer Res. 2011 Sep;8(6):666-77. doi: 10.2174/156720511796717195. Curr Alzheimer Res. 2011. PMID: 21679154 Free PMC article. Review.

8

Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model.

Krishnamurthy PK, Deng Y, Sigurdsson EM. Krishnamurthy PK, et al. Front Psychiatry. 2011 Oct 21;2:59. doi: 10.3389/fpsyt.2011.00059. eCollection 2011. Front Psychiatry. 2011. PMID: 22025915 Free PMC article.

9

In Vivo Validation of a Small Molecule Inhibitor of Tau Self-Association in htau Mice.

Davidowitz EJ, Krishnamurthy PK, Lopez P, Jimenez H, Adrien L, Davies P, Moe JG. Davidowitz EJ, et al. Among authors: krishnamurthy pk. J Alzheimers Dis. 2020;73(1):147-161. doi: 10.3233/JAD-190465. J Alzheimers Dis. 2020. PMID: 31771053 Free PMC article.

10

Therapeutic applications of antibodies in non-infectious neurodegenerative diseases.

Krishnamurthy PK, Sigurdsson EM. Krishnamurthy PK, et al. N Biotechnol. 2011 Sep;28(5):511-7. doi: 10.1016/j.nbt.2011.03.020. Epub 2011 Apr 5. N Biotechnol. 2011. PMID: 21473943 Free PMC article. Review.

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