Sutherland JS - Search Results

1

Investigating serpin-enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II.

Sutherland JS, Bhakta V, Sheffield WP. Sutherland JS, et al. Thromb Res. 2006;117(4):447-61. doi: 10.1016/j.thromres.2005.03.004. Thromb Res. 2006. PMID: 15869786

2

The appended tail region of heparin cofactor II and additional reactive centre loop mutations combine to increase the reactivity and specificity of alpha1-proteinase inhibitor M358R for thrombin.

Sutherland JS, Bhakta V, Sheffield WP. Sutherland JS, et al. Thromb Haemost. 2007 Nov;98(5):1014-23. Thromb Haemost. 2007. PMID: 18000606

3

Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells.

Gierczak RF, Sutherland JS, Bhakta V, Toltl LJ, Liaw PC, Sheffield WP. Gierczak RF, et al. Among authors: sutherland js. J Thromb Haemost. 2011 Dec;9(12):2424-35. doi: 10.1111/j.1538-7836.2011.04524.x. J Thromb Haemost. 2011. PMID: 21972922 Free article.

4

Molecular cloning and functional expression of rabbit alpha2-antiplasmin.

Jobse BN, Sutherland JS, Vaz D, Bhakta V, Sheffield WP. Jobse BN, et al. Among authors: sutherland js. Blood Coagul Fibrinolysis. 2006 Jun;17(4):283-91. doi: 10.1097/01.mbc.0000224848.19754.cc. Blood Coagul Fibrinolysis. 2006. PMID: 16651871

5

The transferable tail: fusion of the N-terminal acidic extension of heparin cofactor II to alpha1-proteinase inhibitor M358R specifically increases the rate of thrombin inhibition.

Sutherland JS, Bhakta V, Filion ML, Sheffield WP. Sutherland JS, et al. Biochemistry. 2006 Sep 26;45(38):11444-52. doi: 10.1021/bi0609624. Biochemistry. 2006. PMID: 16981704

6

HBHA induces IL-10 from CD4+ T cells in patients with active tuberculosis but IFN-γ and IL-17 from individuals with Mycobacterium tuberculosis infection.

Izumida M, Jobe H, Coker EG, Barry A, Rashid M, Manneh IL, Daffeh GK, Ariyoshi K, Sutherland JS. Izumida M, et al. Among authors: sutherland js. Front Immunol. 2024 Aug 27;15:1422700. doi: 10.3389/fimmu.2024.1422700. eCollection 2024. Front Immunol. 2024. PMID: 39257584 Free PMC article.

7

The inclusion of children and adolescents in tuberculosis diagnostic development and evaluation-a consensus statement.

Bijker EM, Horn L, LaCourse S, MacLean EL, Marais BJ, Nicol MP, Olbrich L, Seddon JA, Sutherland JS, Song R, Zar HJ, Jaganath D; Child TB Diagnostics Consensus Group. Bijker EM, et al. Among authors: sutherland js. Lancet Infect Dis. 2024 Nov;24(11):e688-e695. doi: 10.1016/S1473-3099(24)00339-6. Epub 2024 Jul 3. Lancet Infect Dis. 2024. PMID: 38971177 Review.

8

Age and sex influence antibody profiles associated with tuberculosis progression.

Davies LRL, Wang C, Steigler P, Bowman KA, Fischinger S, Hatherill M, Fisher M, Mbandi SK, Rodo M, Ottenhoff THM, Dockrell HM, Sutherland JS, Mayanja-Kizza H, Boom WH, Walzl G, Kaufmann SHE, Nemes E, Scriba TJ, Lauffenburger D, Alter G, Fortune SM. Davies LRL, et al. Among authors: sutherland js. Nat Microbiol. 2024 Jun;9(6):1513-1525. doi: 10.1038/s41564-024-01678-x. Epub 2024 Apr 24. Nat Microbiol. 2024. PMID: 38658786 Free PMC article.

9

Acetic Acid Enables Molecular Enumeration of Mycobacterium tuberculosis from Sputum and Eliminates the Need for a Biosafety Level 3 Laboratory.

Palekyte A, Morkowska A, Billington O, Morris-Jones S, Millard J, Marakalala MJ, Owolabi O, Sambou B, Zumla A, Sutherland JS, McHugh TD, Honeyborne I. Palekyte A, et al. Among authors: sutherland js. Clin Chem. 2024 Apr 3;70(4):642-652. doi: 10.1093/clinchem/hvae013. Clin Chem. 2024. PMID: 38479728

10

Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection.

Nieuwenhuizen NE, Nouailles G, Sutherland JS, Zyla J, Pasternack AH, Heyckendorf J, Frye BC, Höhne K, Zedler U, Bandermann S, Abu Abed U, Brinkmann V, Gutbier B, Witzenrath M, Suttorp N, Zissel G, Lange C, Ritvos O, Kaufmann SHE; CAPNETZ Study group; DZIF TB study group. Nieuwenhuizen NE, et al. Among authors: sutherland js. mBio. 2024 Mar 13;15(3):e0340823. doi: 10.1128/mbio.03408-23. Epub 2024 Feb 20. mBio. 2024. PMID: 38376260 Free PMC article.

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