Cabello C - Search Results

1

Design of novel melanotropin agonists and antagonists with high potency and selectivity for human melanocortin receptors.

Cai M, Mayorov AV, Ying J, Stankova M, Trivedi D, Cabello C, Hruby VJ. Cai M, et al. Among authors: cabello c. Peptides. 2005 Aug;26(8):1481-5. doi: 10.1016/j.peptides.2005.03.020. Peptides. 2005. PMID: 15876475 Review.

2

Biological and conformational study of beta-substituted prolines in MT-II template: steric effects leading to human MC5 receptor selectivity.

Cai M, Cai C, Mayorov AV, Xiong C, Cabello CM, Soloshonok VA, Swift JR, Trivedi D, Hruby VJ. Cai M, et al. Among authors: cabello cm. J Pept Res. 2004 Feb;63(2):116-31. doi: 10.1111/j.1399-3011.2003.00105.x. J Pept Res. 2004. PMID: 15009533

3

Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors.

Kavarana MJ, Trivedi D, Cai M, Ying J, Hammer M, Cabello C, Grieco P, Han G, Hruby VJ. Kavarana MJ, et al. Among authors: cabello c. J Med Chem. 2002 Jun 6;45(12):2644-50. doi: 10.1021/jm020021z. J Med Chem. 2002. PMID: 12036373

4

Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analogues.

Cai M, Mayorov AV, Cabello C, Stankova M, Trivedi D, Hruby VJ. Cai M, et al. Among authors: cabello c. J Med Chem. 2005 Mar 24;48(6):1839-48. doi: 10.1021/jm049579s. J Med Chem. 2005. PMID: 15771429

5

An unusual conformation of γ-melanocyte-stimulating hormone analogues leads to a selective human melanocortin 1 receptor antagonist for targeting melanoma cells.

Cai M, Stankova M, Muthu D, Mayorov A, Yang Z, Trivedi D, Cabello C, Hruby VJ. Cai M, et al. Among authors: cabello c. Biochemistry. 2013 Jan 29;52(4):752-64. doi: 10.1021/bi300723f. Epub 2013 Jan 15. Biochemistry. 2013. PMID: 23276279 Free PMC article.

6

HMGB1-directed drug discovery targeting cutaneous inflammatory dysregulation.

Lamore SD, Cabello CM, Wondrak GT. Lamore SD, et al. Curr Drug Metab. 2010 Mar;11(3):250-65. doi: 10.2174/138920010791196337. Curr Drug Metab. 2010. PMID: 20406187 Review.

7

Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress.

Wondrak GT, Cabello CM, Villeneuve NF, Zhang S, Ley S, Li Y, Sun Z, Zhang DD. Wondrak GT, et al. Free Radic Biol Med. 2008 Aug 15;45(4):385-95. doi: 10.1016/j.freeradbiomed.2008.04.023. Epub 2008 Apr 26. Free Radic Biol Med. 2008. PMID: 18482591 Free PMC article.

8

The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth.

Cabello CM, Bair WB 3rd, Lamore SD, Ley S, Bause AS, Azimian S, Wondrak GT. Cabello CM, et al. Free Radic Biol Med. 2009 Jan 15;46(2):220-31. doi: 10.1016/j.freeradbiomed.2008.10.025. Epub 2008 Nov 1. Free Radic Biol Med. 2009. PMID: 19000754 Free PMC article.

9

Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes.

Qiao S, Lamore SD, Cabello CM, Lesson JL, Muñoz-Rodriguez JL, Wondrak GT. Qiao S, et al. Biochem Pharmacol. 2012 May 1;83(9):1229-40. doi: 10.1016/j.bcp.2012.01.027. Epub 2012 Feb 1. Biochem Pharmacol. 2012. PMID: 22321511 Free PMC article.

10

D-Penicillamine targets metastatic melanoma cells with induction of the unfolded protein response (UPR) and Noxa (PMAIP1)-dependent mitochondrial apoptosis.

Qiao S, Cabello CM, Lamore SD, Lesson JL, Wondrak GT. Qiao S, et al. Apoptosis. 2012 Oct;17(10):1079-94. doi: 10.1007/s10495-012-0746-x. Apoptosis. 2012. PMID: 22843330 Free PMC article.

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