Neschen S - Search Results

1

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.

Hammond LE, Neschen S, Romanelli AJ, Cline GW, Ilkayeva OR, Shulman GI, Muoio DM, Coleman RA. Hammond LE, et al. Among authors: neschen s. J Biol Chem. 2005 Jul 8;280(27):25629-36. doi: 10.1074/jbc.M503181200. Epub 2005 May 6. J Biol Chem. 2005. PMID: 15878874 Free article.

2

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.

Neschen S, Morino K, Hammond LE, Zhang D, Liu ZX, Romanelli AJ, Cline GW, Pongratz RL, Zhang XM, Choi CS, Coleman RA, Shulman GI. Neschen S, et al. Cell Metab. 2005 Jul;2(1):55-65. doi: 10.1016/j.cmet.2005.06.006. Cell Metab. 2005. PMID: 16054099 Free article.

3

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance.

Choi CS, Savage DB, Kulkarni A, Yu XX, Liu ZX, Morino K, Kim S, Distefano A, Samuel VT, Neschen S, Zhang D, Wang A, Zhang XM, Kahn M, Cline GW, Pandey SK, Geisler JG, Bhanot S, Monia BP, Shulman GI. Choi CS, et al. Among authors: neschen s. J Biol Chem. 2007 Aug 3;282(31):22678-88. doi: 10.1074/jbc.M704213200. Epub 2007 May 27. J Biol Chem. 2007. PMID: 17526931 Free article.

4

n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.

Neschen S, Morino K, Dong J, Wang-Fischer Y, Cline GW, Romanelli AJ, Rossbacher JC, Moore IK, Regittnig W, Munoz DS, Kim JH, Shulman GI. Neschen S, et al. Diabetes. 2007 Apr;56(4):1034-41. doi: 10.2337/db06-1206. Epub 2007 Jan 24. Diabetes. 2007. PMID: 17251275

5

Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency.

Zhang D, Christianson J, Liu ZX, Tian L, Choi CS, Neschen S, Dong J, Wood PA, Shulman GI. Zhang D, et al. Among authors: neschen s. Cell Metab. 2010 May 5;11(5):402-11. doi: 10.1016/j.cmet.2010.03.012. Cell Metab. 2010. PMID: 20444420 Free PMC article.

6

Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice.

Neschen S, Morino K, Rossbacher JC, Pongratz RL, Cline GW, Sono S, Gillum M, Shulman GI. Neschen S, et al. Diabetes. 2006 Apr;55(4):924-8. doi: 10.2337/diabetes.55.04.06.db05-0985. Diabetes. 2006. PMID: 16567512

7

Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content.

Neschen S, Moore I, Regittnig W, Yu CL, Wang Y, Pypaert M, Petersen KF, Shulman GI. Neschen S, et al. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E395-401. doi: 10.1152/ajpendo.00414.2001. Am J Physiol Endocrinol Metab. 2002. PMID: 11788372 Free PMC article.

8

Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.

Morino K, Neschen S, Bilz S, Sono S, Tsirigotis D, Reznick RM, Moore I, Nagai Y, Samuel V, Sebastian D, White M, Philbrick W, Shulman GI. Morino K, et al. Among authors: neschen s. Diabetes. 2008 Oct;57(10):2644-51. doi: 10.2337/db06-0454. Epub 2008 Jul 15. Diabetes. 2008. PMID: 18633112 Free PMC article.

9

Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.

Sørensen H, Brand CL, Neschen S, Holst JJ, Fosgerau K, Nishimura E, Shulman GI. Sørensen H, et al. Among authors: neschen s. Diabetes. 2006 Oct;55(10):2843-8. doi: 10.2337/db06-0222. Diabetes. 2006. PMID: 17003351

10

Increased hypothalamic-pituitary-adrenal axis activity and hepatic insulin resistance in low-birth-weight rats.

Buhl ES, Neschen S, Yonemitsu S, Rossbacher J, Zhang D, Morino K, Flyvbjerg A, Perret P, Samuel V, Kim J, Cline GW, Petersen KF. Buhl ES, et al. Among authors: neschen s. Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1451-8. doi: 10.1152/ajpendo.00356.2007. Epub 2007 Sep 25. Am J Physiol Endocrinol Metab. 2007. PMID: 17895287 Free PMC article.

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