Freeman TL - Search Results

1

Aldehydes in cigarette smoke react with the lipid peroxidation product malonaldehyde to form fluorescent protein adducts on lysines.

Freeman TL, Haver A, Duryee MJ, Tuma DJ, Klassen LW, Hamel FG, White RL, Rennard SI, Thiele GM. Freeman TL, et al. Chem Res Toxicol. 2005 May;18(5):817-24. doi: 10.1021/tx0500676. Chem Res Toxicol. 2005. PMID: 15892575

2

Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells.

Duryee MJ, Klassen LW, Freeman TL, Willis MS, Tuma DJ, Thiele GM. Duryee MJ, et al. Among authors: freeman tl. Biochem Pharmacol. 2003 Sep 15;66(6):1045-54. doi: 10.1016/s0006-2952(03)00416-7. Biochem Pharmacol. 2003. PMID: 12963492

3

Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells.

Thiele GM, Duryee MJ, Willis MS, Sorrell MF, Freeman TL, Tuma DJ, Klassen LW. Thiele GM, et al. Among authors: freeman tl. Comp Hepatol. 2004 Jan 14;3 Suppl 1(Suppl 1):S25. doi: 10.1186/1476-5926-2-S1-S25. Comp Hepatol. 2004. PMID: 14960177 Free PMC article. No abstract available.

4

Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity.

Duryee MJ, Willis MS, Freeman TL, Kuszynski CA, Tuma DJ, Klassen LW, Thiele GM. Duryee MJ, et al. Among authors: freeman tl. Front Biosci. 2004 Sep 1;9:3145-55. doi: 10.2741/1467. Front Biosci. 2004. PMID: 15353344 Review.

5

Lipopolysaccharide is a cofactor for malondialdehyde-acetaldehyde adduct-mediated cytokine/chemokine release by rat sinusoidal liver endothelial and Kupffer cells.

Duryee MJ, Klassen LW, Freeman TL, Willis MS, Tuma DJ, Thiele GM. Duryee MJ, et al. Among authors: freeman tl. Alcohol Clin Exp Res. 2004 Dec;28(12):1931-8. doi: 10.1097/01.alc.0000148115.90045.c5. Alcohol Clin Exp Res. 2004. PMID: 15608611

6

Halothane potentiates the alcohol-adduct induced TNF-alpha release in heart endothelial cells.

Thiele GM, Hill GE, Pavlik JA, Freeman TL, Tuma DJ, Duryee MJ, Klassen LW. Thiele GM, et al. Among authors: freeman tl. BMC Anesthesiol. 2005 Apr 12;5(1):3. doi: 10.1186/1471-2253-5-3. BMC Anesthesiol. 2005. PMID: 15826301 Free PMC article.

7

Recent advances in alcohol-induced adduct formation.

Freeman TL, Tuma DJ, Thiele GM, Klassen LW, Worrall S, Niemelä O, Parkkila S, Emery PW, Preedy VR. Freeman TL, et al. Alcohol Clin Exp Res. 2005 Jul;29(7):1310-6. doi: 10.1097/01.alc.0000171484.52201.52. Alcohol Clin Exp Res. 2005. PMID: 16088993 No abstract available.

8

Scavenger receptors on sinusoidal liver endothelial cells are involved in the uptake of aldehyde-modified proteins.

Duryee MJ, Freeman TL, Willis MS, Hunter CD, Hamilton BC 3rd, Suzuki H, Tuma DJ, Klassen LW, Thiele GM. Duryee MJ, et al. Among authors: freeman tl. Mol Pharmacol. 2005 Nov;68(5):1423-30. doi: 10.1124/mol.105.016121. Epub 2005 Aug 16. Mol Pharmacol. 2005. PMID: 16105988

9

Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol.

Thiele GM, Duryee MJ, Freeman TL, Sorrell MF, Willis MS, Tuma DJ, Klassen LW. Thiele GM, et al. Among authors: freeman tl. Biochem Pharmacol. 2005 Nov 25;70(11):1593-600. doi: 10.1016/j.bcp.2005.08.014. Epub 2005 Oct 3. Biochem Pharmacol. 2005. PMID: 16202982

10

Inhibition of hepatic stellate cell collagen synthesis by N-(methylamino)isobutyric acid.

Freeman TL, Kharbanda KK, Tuma DJ, Mailliard ME. Freeman TL, et al. Biochem Pharmacol. 2002 Feb 15;63(4):697-706. doi: 10.1016/s0006-2952(01)00885-1. Biochem Pharmacol. 2002. PMID: 11992638

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