Meli M - Search Results

1

Rational design of shepherdin, a novel anticancer agent.

Plescia J, Salz W, Xia F, Pennati M, Zaffaroni N, Daidone MG, Meli M, Dohi T, Fortugno P, Nefedova Y, Gabrilovich DI, Colombo G, Altieri DC. Plescia J, et al. Among authors: meli m. Cancer Cell. 2005 May;7(5):457-68. doi: 10.1016/j.ccr.2005.03.035. Cancer Cell. 2005. PMID: 15894266 Free article.

2

Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.

Gyurkocza B, Plescia J, Raskett CM, Garlick DS, Lowry PA, Carter BZ, Andreeff M, Meli M, Colombo G, Altieri DC. Gyurkocza B, et al. Among authors: meli m. J Natl Cancer Inst. 2006 Aug 2;98(15):1068-77. doi: 10.1093/jnci/djj300. J Natl Cancer Inst. 2006. PMID: 16882944

3

Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead.

Meli M, Pennati M, Curto M, Daidone MG, Plescia J, Toba S, Altieri DC, Zaffaroni N, Colombo G. Meli M, et al. J Med Chem. 2006 Dec 28;49(26):7721-30. doi: 10.1021/jm060836y. J Med Chem. 2006. PMID: 17181154

4

Computational studies of the structure, dynamics and native content of amyloid-like fibrils of ribonuclease A.

Colombo G, Meli M, De Simone A. Colombo G, et al. Among authors: meli m. Proteins. 2008 Feb 15;70(3):863-72. doi: 10.1002/prot.21648. Proteins. 2008. PMID: 17803210

5

Investigating the mechanism of peptide aggregation: insights from mixed monte carlo-molecular dynamics simulations.

Meli M, Morra G, Colombo G. Meli M, et al. Biophys J. 2008 Jun;94(11):4414-26. doi: 10.1529/biophysj.107.121061. Epub 2008 Feb 8. Biophys J. 2008. PMID: 18263661 Free PMC article.

6

Molecular dynamics simulations of proteins and peptides: from folding to drug design.

Morra G, Meli M, Colombo G. Morra G, et al. Among authors: meli m. Curr Protein Pept Sci. 2008 Apr;9(2):181-96. doi: 10.2174/138920308783955234. Curr Protein Pept Sci. 2008. PMID: 18393887 Review.

7

Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution.

Colombo G, Morra G, Meli M, Verkhivker G. Colombo G, et al. Among authors: meli m. Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):7976-81. doi: 10.1073/pnas.0802879105. Epub 2008 May 29. Proc Natl Acad Sci U S A. 2008. PMID: 18511558 Free PMC article.

8

Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90.

Kang BH, Plescia J, Song HY, Meli M, Colombo G, Beebe K, Scroggins B, Neckers L, Altieri DC. Kang BH, et al. Among authors: meli m. J Clin Invest. 2009 Mar;119(3):454-64. doi: 10.1172/JCI37613. Epub 2009 Feb 23. J Clin Invest. 2009. PMID: 19229106 Free PMC article.

9

Molecular simulations of peptides: a useful tool for the development of new drugs and for the study of molecular recognition.

Meli M, Colombo G. Meli M, et al. Methods Mol Biol. 2009;570:77-153. doi: 10.1007/978-1-60327-394-7_4. Methods Mol Biol. 2009. PMID: 19649590 Review.

10

Combined in silico and experimental approach for drug design: the binding mode of peptidic and non-peptidic inhibitors to hsp90 N-terminal domain.

Tomaselli S, Meli M, Plescia J, Zetta L, Altieri DC, Colombo G, Ragona L. Tomaselli S, et al. Among authors: meli m. Chem Biol Drug Des. 2010 Nov;76(5):382-91. doi: 10.1111/j.1747-0285.2010.01015.x. Chem Biol Drug Des. 2010. PMID: 20925690 Free PMC article.

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