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Matrix metalloproteinase-activated doxorubicin prodrugs inhibit HT1080 xenograft growth better than doxorubicin with less toxicity.
Albright CF, Graciani N, Han W, Yue E, Stein R, Lai Z, Diamond M, Dowling R, Grimminger L, Zhang SY, Behrens D, Musselman A, Bruckner R, Zhang M, Jiang X, Hu D, Higley A, Dimeo S, Rafalski M, Mandlekar S, Car B, Yeleswaram S, Stern A, Copeland RA, Combs A, Seitz SP, Trainor GL, Taub R, Huang P, Oliff A. Albright CF, et al. Among authors: behrens d. Mol Cancer Ther. 2005 May;4(5):751-60. doi: 10.1158/1535-7163.MCT-05-0006. Mol Cancer Ther. 2005. PMID: 15897239
Phospholipase C inhibitors: a new class of cytotoxic agents.
Perrella FW, Chen SF, Behrens DL, Kaltenbach RF 3rd, Seitz SP. Perrella FW, et al. Among authors: behrens dl. J Med Chem. 1994 Jul 8;37(14):2232-7. doi: 10.1021/jm00040a016. J Med Chem. 1994. PMID: 8035430
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
Kirshenbaum MR, Chen SF, Behrens CH, Papp LM, Stafford MM, Sun JH, Behrens DL, Fredericks JR, Polkus ST, Sipple P, et al. Kirshenbaum MR, et al. Among authors: behrens dl, behrens ch. Cancer Res. 1994 Apr 15;54(8):2199-206. Cancer Res. 1994. PMID: 8174127
XB596, a promising bis-naphthalimide anti-cancer agent.
Chen SF, Behrens DL, Behrens CH, Czerniak PM, Dexter DL, Dusak BL, Fredericks JR, Gale KC, Gross JL, Jiang JB, et al. Chen SF, et al. Among authors: behrens dl, behrens ch. Anticancer Drugs. 1993 Aug;4(4):447-57. doi: 10.1097/00001813-199308000-00005. Anticancer Drugs. 1993. PMID: 8400347
Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer.
Veghini L, Pasini D, Fang R, Delfino P, Filippini D, Neander C, Vicentini C, Fiorini E, Lupo F, D'Agosto SL, Carbone C, Agostini A, Piro G, Rosa D, Bevere M, Markus P, Behrens D, Luchini C, Lawlor RT, Scarpa A, Biffi G, Cheung PF, Siveke JT, Corbo V. Veghini L, et al. Among authors: behrens d. Nat Commun. 2024 Dec 3;15(1):10534. doi: 10.1038/s41467-024-54975-8. Nat Commun. 2024. PMID: 39627211 Free PMC article.
118 results