Yan Y - Search Results

1

Expression of kinase suppressor of Ras1 enhances cisplatin-induced extracellular signal-regulated kinase activation and cisplatin sensitivity.

Kim M, Yan Y, Kortum RL, Stoeger SM, Sgagias MK, Lee K, Lewis RE, Cowan KH. Kim M, et al. Among authors: yan y. Cancer Res. 2005 May 15;65(10):3986-92. doi: 10.1158/0008-5472.CAN-03-2334. Cancer Res. 2005. PMID: 15899786

2

The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells.

Kim M, Turnquist H, Jackson J, Sgagias M, Yan Y, Gong M, Dean M, Sharp JG, Cowan K. Kim M, et al. Among authors: yan y. Clin Cancer Res. 2002 Jan;8(1):22-8. Clin Cancer Res. 2002. PMID: 11801536

3

BRCA1-induced apoptosis involves inactivation of ERK1/2 activities.

Yan Y, Haas JP, Kim M, Sgagias MK, Cowan KH. Yan Y, et al. J Biol Chem. 2002 Sep 6;277(36):33422-30. doi: 10.1074/jbc.M201147200. Epub 2002 Jun 24. J Biol Chem. 2002. Retraction in: J Biol Chem. 2019 May 17;294(20):8309. doi: 10.1074/jbc.W119.009053 PMID: 12082091 Free article. Retracted.

4

Ectopic expression of von Hippel-Lindau tumor suppressor induces apoptosis in 786-O renal cell carcinoma cells and regresses tumor growth of 786-O cells in nude mouse.

Kim M, Yan Y, Lee K, Sgagias M, Cowan KH. Kim M, et al. Among authors: yan y. Biochem Biophys Res Commun. 2004 Jul 30;320(3):945-50. doi: 10.1016/j.bbrc.2004.06.042. Biochem Biophys Res Commun. 2004. PMID: 15240140

5

BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.

Yan Y, Spieker RS, Kim M, Stoeger SM, Cowan KH. Yan Y, et al. Oncogene. 2005 May 5;24(20):3285-96. doi: 10.1038/sj.onc.1208492. Oncogene. 2005. PMID: 15735702

6

Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.

Yan Y, Black CP, Cowan KH. Yan Y, et al. Oncogene. 2007 Jul 12;26(32):4689-98. doi: 10.1038/sj.onc.1210268. Epub 2007 Feb 5. Oncogene. 2007. PMID: 17297454

7

Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1.

Yan Y, Black CP, Cao PT, Haferbier JL, Kolb RH, Spieker RS, Ristow AM, Cowan KH. Yan Y, et al. Cancer Res. 2008 Jul 1;68(13):5113-21. doi: 10.1158/0008-5472.CAN-07-5818. Cancer Res. 2008. PMID: 18593910 Free PMC article.

8

Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response.

Yan Y, Cao PT, Greer PM, Nagengast ES, Kolb RH, Mumby MC, Cowan KH. Yan Y, et al. Oncogene. 2010 Jul 29;29(30):4317-29. doi: 10.1038/onc.2010.187. Epub 2010 May 24. Oncogene. 2010. PMID: 20498628 Free PMC article.

9

RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation.

Yan Y, Greer PM, Cao PT, Kolb RH, Cowan KH. Yan Y, et al. Breast Cancer Res. 2012 Apr 11;14(2):R60. doi: 10.1186/bcr3164. Breast Cancer Res. 2012. PMID: 22494620 Free PMC article.

10

Inhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal therapeutic option.

Pessetto ZY, Yan Y, Bessho T, Natarajan A. Pessetto ZY, et al. Among authors: yan y. Breast Cancer Res Treat. 2012 Jul;134(2):511-7. doi: 10.1007/s10549-012-2079-4. Epub 2012 May 6. Breast Cancer Res Treat. 2012. PMID: 22562176 Free PMC article.

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