Zhang X - Search Results

1

Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: synthesis and biological activity.

Bacherikov VA, Chou TC, Dong HJ, Zhang X, Chen CH, Lin YW, Tsai TJ, Lee RZ, Liu LF, Su TL. Bacherikov VA, et al. Among authors: zhang x. Bioorg Med Chem. 2005 Jun 2;13(12):3993-4006. doi: 10.1016/j.bmc.2005.03.057. Bioorg Med Chem. 2005. PMID: 15911312

2

Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity.

Su TL, Lin YW, Chou TC, Zhang X, Bacherikov VA, Chen CH, Liu LF, Tsai TJ. Su TL, et al. Among authors: zhang x. J Med Chem. 2006 Jun 15;49(12):3710-8. doi: 10.1021/jm060197r. J Med Chem. 2006. PMID: 16759114

3

Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.

Kapuriya N, Kapuriya K, Zhang X, Chou TC, Kakadiya R, Wu YT, Tsai TH, Chen YT, Lee TC, Shah A, Naliapara Y, Su TL. Kapuriya N, et al. Among authors: zhang x. Bioorg Med Chem. 2008 May 15;16(10):5413-23. doi: 10.1016/j.bmc.2008.04.024. Epub 2008 Apr 15. Bioorg Med Chem. 2008. PMID: 18450456

4

Synthesis and in vitro cytotoxicity of 9-anilinoacridines bearing N-mustard residue on both anilino and acridine rings.

Chen CH, Lin YW, Zhang X, Chou TC, Tsai TJ, Kapuriya N, Kakadiya R, Su TL. Chen CH, et al. Among authors: zhang x. Eur J Med Chem. 2009 Jul;44(7):3056-9. doi: 10.1016/j.ejmech.2008.07.016. Epub 2008 Jul 22. Eur J Med Chem. 2009. PMID: 18752869

5

Novel DNA-directed alkylating agents: design, synthesis and potent antitumor effect of phenyl N-mustard-9-anilinoacridine conjugates via a carbamate or carbonate linker.

Kapuriya N, Kapuriya K, Dong H, Zhang X, Chou TC, Chen YT, Lee TC, Lee WC, Tsai TH, Naliapara Y, Su TL. Kapuriya N, et al. Among authors: zhang x. Bioorg Med Chem. 2009 Feb 1;17(3):1264-75. doi: 10.1016/j.bmc.2008.12.022. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19124250

6

Potent antitumor bifunctional DNA alkylating agents, synthesis and biological activities of 3a-aza-cyclopenta[a]indenes.

Kakadiya R, Dong H, Lee PC, Kapuriya N, Zhang X, Chou TC, Lee TC, Kapuriya K, Shah A, Su TL. Kakadiya R, et al. Among authors: zhang x. Bioorg Med Chem. 2009 Aug 1;17(15):5614-26. doi: 10.1016/j.bmc.2009.06.018. Epub 2009 Jun 16. Bioorg Med Chem. 2009. PMID: 19576785

7

Potent DNA-directed alkylating agents: Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linker.

Kakadiya R, Dong H, Kumar A, Narsinh D, Zhang X, Chou TC, Lee TC, Shah A, Su TL. Kakadiya R, et al. Among authors: zhang x. Bioorg Med Chem. 2010 Mar 15;18(6):2285-2299. doi: 10.1016/j.bmc.2010.01.061. Epub 2010 Feb 4. Bioorg Med Chem. 2010. PMID: 20181487

8

Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents.

Kapuriya N, Kakadiya R, Dong H, Kumar A, Lee PC, Zhang X, Chou TC, Lee TC, Chen CH, Lam K, Marvania B, Shah A, Su TL. Kapuriya N, et al. Among authors: zhang x. Bioorg Med Chem. 2011 Jan 1;19(1):471-85. doi: 10.1016/j.bmc.2010.11.005. Epub 2010 Nov 5. Bioorg Med Chem. 2011. PMID: 21106377

9

Synthesis and structure-activity relationships of potential anticancer agents: alkylcarbamates of 3-(9-acridinylamino)-5-hydroxymethylaniline.

Su TL, Chen CH, Huang LF, Chen CH, Basu MK, Zhang XG, Chou TC. Su TL, et al. Among authors: zhang xg. J Med Chem. 1999 Nov 18;42(23):4741-8. doi: 10.1021/jm9901226. J Med Chem. 1999. PMID: 10579838

10

Therapeutic cure against human tumor xenografts in nude mice by a microtubule stabilization agent, fludelone, via parenteral or oral route.

Chou TC, Dong H, Zhang X, Tong WP, Danishefsky SJ. Chou TC, et al. Among authors: zhang x. Cancer Res. 2005 Oct 15;65(20):9445-54. doi: 10.1158/0008-5472.CAN-05-1014. Cancer Res. 2005. PMID: 16230408

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